Highlighting side effects, warnings, interactions, and more
« Wellbutrin’s Uses and Using | Wellbutrin’s Pros and Cons »
|US brand name: Wellbutrin|
| Generic name: bupropion |
Wellbutrin’s Potential Side Effects
Potential Side Effects All Crazy Meds Have
No matter which neurological and/or psychiatric drug you take, you’ll probably get one or more of these side effects. These will usually be gone, or at least will diminish to the point where you barely notice it most of the time, within a week or two.
- Drowsiness / fatigue - even when taking stimulants in some circumstances.
- Insomnia, instead of or alternating with the drowsiness.
- Assorted other minor GI complaints (constipation, diarrhea, etc.)
- Generally feeling spacey / out of it
- Which can all add up to the ever-helpful “flu-like symptoms” listed as an adverse event on the PI sheet of practically every medication on the planet used to treat almost any condition humans and other animals could have.1
- All crazy meds can, and probably will affect your dreams as well. There is no way of telling if that will be good or bad, let alone if this side effect is permanent or temporary.
- Any of the above side effects you see listed again below means they’re even more likely to happen and/or stick around longer and/or are worse than most other meds.
Typical Potential Side Effects
, weight loss
(it’s undergone trials both as, and part of, a weight loss medication), headache
, dry mouth
. Most of these are transitory, but the weight loss, agitation and insomnia tend to stick around.
Uncommon Potential Side Effects
Strange body odor
. Basically it could make you look like the guilty party, so you better have a damn good alibi at all times in case some big, unsolved crime goes down. Also: seizures
Freaky Rare Side Effects
Change in hair color
. They swore Lady Clairol wasn’t involved! There was also new hair, possibly in unusual places
. Painful erections
, unusual ejaculations
, and outright impotence
. You know you’re the butt of one of God’s little jokes if you become impotent or get one or more of the dick-pain side effects and
Not all side effects have been listed here, just the most likely and most interesting. For all reported side effects, see Wellbutrin’s PI Sheet.
What You Really Need to be Careful About
Seizures, especially if you’ve either had seizures before (thank you Dr. Obvious), an eating disorder, or have recently stopped drinking a shitload of booze every day.
Wellbutrin’s Noted Drug-Drug, Drug-Food & Drug-Supplement Interactions
SSRIs. You’d think taking an SSRI and bupropion would be a great idea, as you get all three of the popular neurotransmitters in a home-brewed triple reuptake inhibitor, right? Unfortunately fluoxetine, fluvoxamine, sertraline, and paroxetine all inhibit CYP2B6, which affects the transformation of bupropion to its active metabolites as well as its elimination. And citalopram and escitalopram are eliminated by CYP2D6, so that makes their dosages tricky.
And tamoxifen, of course, as bupropion is a potent CYP2D6 inhibitor.
Wellbutrin + ECT = mania, even if you’re not bipolar. At least there’s a fair chance of mania even if you’re not bipolar, so it’s something to be aware of when you’re feeling lower than whaleshit on the bottom of the ocean.
Check for Other Drug-Drug, Drug-Food & Drug-Supplement Interactions Wellbutrin may have at
Drugs.com’s drug-drug and drug-food interaction checker
It’s always a good idea to check for drug-drug interactions yourself. Just because most people in the crazy meds business know about really important interactions (e.g. MAOIs and a lot of stuff, warfarin and everything on the planet) doesn’t mean the person who prescribed your meds told you about them, or the pharmacist has all the meds you take at their fingertips like they’re supposed to. Or they have the time to do their jobs properly when not dealing with complete idiots or playing Angry Farmers on teh Faecesbooks.
Learn more about drug-everything interactions on our page of tips about taking crazy meds.
Pages and Forum Topics Google Thinks are Relevant to Your Mental Health
1 As well as being an indication of half of said conditions.
|Last modified on Wed, 04 May, 2016 at 18:00:59 by JerodPoore||Page Author Jerod Poore||Date created 27 March 2011 at 14:50:23|
|“Wellbutrin (bupropion) Pharmacology” by Jerod Poore is copyright © 2011 Jerod Poore ||Published online 2011/03/27|
Wellbutrin, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Wellbutrin’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.
Page design and explanatory material by Jerod Poore, copyright © 2003 - 2016. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.
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