Highlighting side effects, warnings, interactions, and more


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US brand name: Remeron
Generic name: mirtazapine

Remeron’s Potential Side Effects

Potential Side Effects All Crazy Meds Have

No matter which neurological and/or psychiatric drug you take, you’ll probably get one or more of these side effects. These will usually be gone, or at least will diminish to the point where you barely notice it most of the time, within a week or two.

  • Headache
  • Drowsiness / fatigue - even when taking stimulants in some circumstances.
  • Insomnia, instead of or alternating with the drowsiness.
  • Nausea
  • Assorted other minor GI complaints (constipation, diarrhea, etc.)
  • Generally feeling spacey / out of it
    • Which can all add up to the ever-helpful “flu-like symptoms” listed as an adverse event on the PI sheet of practically every medication on the planet used to treat almost any condition humans and other animals could have.1
  • All crazy meds can, and probably will affect your dreams as well. There is no way of telling if that will be good or bad, let alone if this side effect is permanent or temporary.
  • Any of the above side effects you see listed again below means they’re even more likely to happen and/or stick around longer and/or are worse than most other meds.

Typical Potential Side Effects

Most of the anticholinergic effects common with psychiatric medications (e.g. constipation, confusion, loss of coordination, memory loss) are infrequent. Instead you get intense hunger for the wrong foods, and with that comes weight gain, dry mouth and constipation caused by what you eat and not the drug itself. Then you want to sleep a lot. It’s like you may as well be smoking pot. Except usually less fun. While Remeron could make your bipolar disorder (or schizophrenia) somewhat worse in the short run by triggering a manic reaction, it won’t make it a lot, and permanently, worse like cannabis will2.

Uncommon Potential Side Effects

Edema, dizziness, low blood pressure, increased thirst to go with the munchies, flu-like symptoms.

Freaky Rare Side Effects

Going deaf and various flavors of herpes. Yeah, right, it was the Remeron that gave someone that STD. (See this review for how the herpes thing really works.) The deafness (the PI sheet doesn’t indicate to what extent or for how long) is an example of my “side effects are sometimes like allergies” corollary to the “allergies are leftover immune responses to diseases that no longer exist” hypothesis. But only if you consider the case studies referenced above about using Remeron to treat auditory hallucinations. It’s not as strong a connection as the one for the whole-body muscle aches caused by Topamax and Lamictal being related to how well they treat atonic (drop) seizures.

Not all side effects have been listed here, just the most likely and most interesting. For all reported side effects, see Remeron’s PI Sheet.

What You Really Need to be Careful About

Remeron also carries a warning for agranulyocytosis, the severe reduction in white cell count, along with fever, infection and all that fun stuff. That hit Mouse like a ton of bricks. She was stuck in a motel in Fairfield for a week after one dose.

Pregnancy Category

Remeron’s Noted Drug-Drug, Drug-Food & Drug-Supplement Interactions

Check for Other Drug-Drug, Drug-Food & Drug-Supplement Interactions Remeron may have at

Drugs.com’s drug-drug and drug-food interaction checker

It’s always a good idea to check for drug-drug interactions yourself. Just because most people in the crazy meds business know about really important interactions (e.g. MAOIs and a lot of stuff, warfarin and everything on the planet) doesn’t mean the person who prescribed your meds told you about them, or the pharmacist has all the meds you take at their fingertips like they’re supposed to. Or they have the time to do their jobs properly when not dealing with complete idiots or playing Angry Farmers on teh Faecesbooks.
Learn more about drug-everything interactions on our page of tips about taking crazy meds.

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Pages and Forum Topics Google Thinks are Relevant to Your Mental Health

1 As well as being an indication of half of said conditions.

2 I write from experience regarding pot. If you're bipolar or schizophrenic avoid it at all costs. Don't end up with treatment-resistant bipolar disorder like me, or dead from schizophrenia like my brother-in-law. For the 90% of the population who doesn't have severe brain cooties: smoke all you want. Within reason.

Last modified on Wed, 04 May, 2016 at 17:53:34 by JerodPoorePage Author Date created Mon, 25 Apr, 2011
“Remeron (mirtazapine) Pharmacology” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/04/25

Remeron, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Remeron’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

Page design and explanatory material by Jerod Poore, copyright © 2003 - 2016. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.

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