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‹< Lexapro’s Pharmacology |

US brand name: Lexapro
Generic name: escitalopram

Comments

Lexapro is probably the best-tolerated and most effective SSRI currently on the market. Mainly because it’s just a little better than Celexa (citalopram). Celexa was chosen as the first antidepressant used in the massive STAR*D study for being the best-tolerated SSRI and was considered the most effective. Lexapro was too new at the time. Is Celexa really more effective than all the other SSRIs? Yes, but not by all that much. It did rather well in the STAR*D study, with almost half the people responding, but a third of them relapsing. However, by sucking a lot less than the others, people keep taking Celexa and that makes it far more effective in the long run. The same is true for Lexapro. It sucks less, so people keep taking it.

Another thing Lexapro does well is preventing relapses.

Outside of the US Lexapro, as Cipralex and other brand names, is approved for a lot of conditions in the panic-anxiety spectrum. The data in some of the clinical trials I could find seem a bit dodgy, but there is no doubt that Lexapro works for most anxiety conditions. This raises a bit of a conundrum. I’d like to see a streamlining of the approval process for meds with overseas approvals. If a drug is already approved in the US, as Lexapro is, and is approved to treat other conditions in places like the UK, the EU, Canada, Australia, and Japan1, it should be really easy to get the med approved by the FDA to treat those conditions. The EU has higher standards than the US to get a med approved - the main one being not using a placebo to compare a new med with, but an existing med used to treat whatever the new med treats. But if the overseas approval is a little hinky, then it’s not much different from what happens here sometimes. Then again, if the med works and it’s not killing anyone, it’s a good thing, right? It’s like what you see on cop shows all the time. With nothing more than a hunch and tip from an unreliable source, some cops break down some doors and destroy a meth lab. Nobody wants meth labs in their neighborhood, but they don’t want the cops breaking down doors whenever they feel like it.

Name, Address, Serial Number (Generic and Overseas Availability)

Available in the US as a generic? Yes

Shapes & Sizes (How Supplied)

In the US: 5 mg tablets , 10 mg tablets , 20 mg tablets , oral solution

Most EU countries have both tablets and capsules, a 15mg tablet/capsule, and premeasured 1ml, 5ml, 10ml and 20ml dosages of the oral solution. There’s an orally dissoluble (Cipralex orodispersible) tablet available in Sweden and the UK.



Other Trade Names and Overseas Availability

Not including controlled/extended/sustained release suffixes (Efexor ER, Trevilor retard e.g.) or branded generics that are a hyphenate of the generic name and the drug company name (Apo-Citalopram e.g.).

Available as Lexapro in These Countries

Argentina, Australia, Brazil, Chile, Colombia, Hong Kong, Ireland, New Zealand, Peru, Philippines, Singapore, Thailand

Available as Generic Escitalopram in These Countries

Australia, Argentina, Canada, Chile, the EU.

Transliterated, Overseas Trade and Branded Generic Names

  • Argentina: Esertia , Meridian
  • Australia: Esipram , Esitalo , Lexam , Loxalate
  • Chile: CELTIUM , ECIPRAX , ECTIBAN , IPRAN , NEOPRESOL , NEOZENTIUS , REPOSIL , ZEPAZ Comprimidos
  • Spain: Esertia
  • essitalopraami is Finnish for escitalopram

Full US PI sheet, Global SPCs & PILs, Other Consumer Review & Rating Sites, and Other Sites that may be of Interest

Lexapro’s Full US Prescribing Information / PI Sheet

Official Sites

PI Sheets from Around the World

Rating & Review Sites

Other Sites of Interest

DrugsDB.com Lexapro page



Discussion board

If you have any questions not answered here, please see the Crazymeds Lexapro discussion board.

References

  1. Lexapro’s Full US Prescribing Information
  2. Faught, Edward. “Topiramate in the treatment of partial and generalized epilepsy.” Neuropsychiatric disease and treatment 3.6 (2007): 811-821.
  3. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Third edition ISBN:978-0521673761 by Stephen M. Stahl © 2008 Published by Cambridge University Press.
  4. Primer of Drug Action 12th edition by Robert M. Julien Ph.D, Claire D. Advokat, Joseph Comaty © 2011 ISBN:978-1429233439 Published by Worth Publishers.
  5. The Prescriber’s Guide (Essential Psychopharmacology Series) Third edition by Stephen Stahl © 2009 Published by Cambridge University Press.
  6. Clinical Handbook of Psychotropic Drugs 18th edition Adil S. Virani, K. Bezchlibnyk-Butler, J. Jeffries © 2009 Published by Hogrefe & Huber Publishers.
  7. Mosby’s Drug Consult 2007 (Generic Prescription Physician’s Reference Book Series) © 2007 An imprint of Elsevier.
  8. PDR: Physicians’ Desk Reference 2010 64th edition
  9. The therapeutic potential of escitalopram in the treatment of panic disorder

‹< Lexapro’s Pharmacology |

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Last modified on Wed, 04 May, 2016 at 16:45:52 by JerodPoorePage Author Date created Sunday, 05 December 2010 at 13:49
“Lexapro (escitalopram): Availability, Comments, Links, More” by Jerod Poore is copyright © 2010 Jerod Poore Published online 2010/12/05

Lexapro, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Lexapro’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



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