Highlighting side effects, warnings, interactions, and more

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US brand name: Latuda
Generic name: lurasidone

Latuda’s Potential Side Effects

Potential Side Effects All Crazy Meds Have

No matter which neurological and/or psychiatric drug you take, you’ll probably get one or more of these side effects. These will usually be gone, or at least will diminish to the point where you barely notice it most of the time, within a week or two.

  • Headache
  • Drowsiness / fatigue - even when taking stimulants in some circumstances.
  • Insomnia, instead of or alternating with the drowsiness.
  • Nausea
  • Assorted other minor GI complaints (constipation, diarrhea, etc.)
  • Generally feeling spacey / out of it
    • Which can all add up to the ever-helpful “flu-like symptoms” listed as an adverse event on the PI sheet of practically every medication on the planet used to treat almost any condition humans and other animals could have.1
  • All crazy meds can, and probably will affect your dreams as well. There is no way of telling if that will be good or bad, let alone if this side effect is permanent or temporary.
  • Any of the above side effects you see listed again below means they’re even more likely to happen and/or stick around longer and/or are worse than most other meds.


Typical Potential Side Effects

Movement disorders . Movement disorders galore. 20–40% of the people in the clinical trials had some form of movement disorder, mainly akathisia (severe, overwhelming restlessness) and the rate of side effects in clinical trials are almost always lower than real life.

Nausea and other GI problems are common, but that’s often the case with any made you really need to take with food. Putting you to sleep (somnolence) and making you feel tired throughout the day (lethargy, sedation) are also common, but Latuda’s an antipsychotic, so what can you expect? Since Latuda is used to treat depression insomnia and anxiety are popular side effects.

Uncommon Potential Side Effects

Freaky Rare Side Effects

Glossopharyngeal dystonia - which is a combination of slurred speech and barely being able to breathe. The only reason this guy had it is because his doctor and pharmacist were both incompetent and failed to notice the drug-drug interaction of Prozac and Latuda.

Not all side effects have been listed here, just the most likely and most interesting. For all reported side effects, see Latuda’s PI Sheet.



What You Really Need to be Careful About

Do not even look at Prozac (fluoxetine), Luvox (fluvoxamine), nefazodone, carbamazepine, grapefruit juice, pomegranate juice, anything containing grapefruit or pomegranate, or anything else that affects CYP3A4.

Pregnancy Category

B-proven safe, but not as well tested as A

Latuda’s Noted Drug-Drug, Drug-Food & Drug-Supplement Interactions

Don’t even think about drinking grapefruit juice , pomegranate juice , eating grapefruits juice , or pomegranates , or anything else discussed on our page about such things. That goes double for taking meds that inhibit or induce CYP3A4. So if your doctor prescribes you Latuda when you’re taking one or more of the following:

then you need a new doctor. Unless you didn’t tell your doctor about the St. John’s wort. In which case you’re a moron and have no one to blame but yourself if the Latuda doesn’t work. The same goes for your pharmacist if they have all of what you’re taking in their database. There are also a bunch of non-crazy meds involved, but that’s why God invented drug-drug interaction checkers.

Check for Other Drug-Drug, Drug-Food & Drug-Supplement Interactions Latuda may have at

Drugs.com’s drug-drug and drug-food interaction checker

It’s always a good idea to check for drug-drug interactions yourself. Just because most people in the crazy meds business know about really important interactions (e.g. MAOIs and a lot of stuff, warfarin and everything on the planet) doesn’t mean the person who prescribed your meds told you about them, or the pharmacist has all the meds you take at their fingertips like they’re supposed to. Or they have the time to do their jobs properly when not dealing with complete idiots or playing Angry Farmers on teh Faecesbooks.
Learn more about drug-everything interactions on our page of tips about taking crazy meds.



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1 As well as being an indication of half of said conditions.


Last modified on Wed, 04 May, 2016 at 17:23:40 by JerodPoorePage Author Date created Tuesday, 14 May 2013 at 09:18:44
“Latuda (lurasidone) Pharmacology” by Jerod Poore is copyright © 2013 Jerod Poore Published online 2013/05/14

Latuda, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Latuda’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



Page design and explanatory material by Jerod Poore, copyright © 2003 - 2016. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.

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