‹< Lamictal’s Pharmacology |
|US brand name: Lamictal|
| Generic name: lamotrigine |
Antiepileptic drugs / anticonvulsants (AEDs / ACs) are generally a pain in the ass to take, and Lamictal is the biggest diva of them all. But it works, and works well, for two difficult-to-treat conditions: bipolar 2 featuring severe, near-constant depression that is usually misdiagnosed as a variant of unipolar depression, and Lennox-Gastaut syndrome.
Crazy meds are an exercise in patience. You need to wait for side effects to go away. You need to wait for the meds to start working. In The Prescriber’s Guide (Essential Psychopharmacology Series) Stahl has “Wait. Wait. Wait.” as the first three things to try in order to deal with side effects that he must of had a keyboard macro for it. Lamictal, being Lamictal, has to be the most extreme when it comes to that by requiring you to have your symptoms under control by another medication before starting. At least if you want to have the best chance for Lamictal to work. The idea is for Lamictal to replace whatever you’re taking.
You may have to drastically alter your lifestyle and that of your entire family (e.g. no more perfume or scented cleaning products) to keep taking it without being covered in a scary-looking, but otherwise benign rash, but that sucks so much less than treatment-resistant bipolar 2 or watching your kid with Lennox-Gastaut hit the floor for the twentieth time today. See the extended comments and detailed side effects pages for more information on Lamictal’s interaction with fragrances.
In spite of the climate of fear that permeates everything having to do with it because of The Rash, and loud complaints about killer headaches and full-body muscle aches, Lamictal actually has one of the lowest side effect profiles around. It’s not as low as Keppra’s but it is almost as low as Neurontin’s, with the added advantage of actually doing something for bipolar disorder and forms of epilepsy that are usually way too severe for Neurontin to handle. It may be the pickiest of all AEDs, but has been an absolute lifesaver for thousands of people.
Name, Address, Serial Number (Generic and Overseas Availability)
Available in the US as a generic? Yes
Shapes & Sizes (How Supplied)
- Difficult-to-swallow, shield-shaped, immediate-release Lamictal:
- 25 mg tablets
- 100 mg tablets
- 150 mg tablets
- 200 mg tablets
- Generic lamotrigine comes in various shapes (see pictures below)
- Lamictal ODT:
- 25 mg orally disintegrating tablets
- 50 mg orally disintegrating tablets
- 100 mg orally disintegrating tablets
- 200 mg orally disintegrating tablets
- Lamictal Chewable:
- 2 mg chewable dispersible tablets
- 5 mg chewable dispersible tablets
- 25 mg chewable dispersible tablets
- Lamictal-XR (round with a white center):
- 25 mg extended-release tablets
- 100 mg extended-release tablets
- 150 mg extended-release tablets
- 200 mg extended-release tablets
- 300 mg extended-release tablets
Left: Brand Lamictal 25 mg Tablets. Right: Teva Generic Lamotrigine 25 mg Tablets.
Left: Teva Generic Lamotrigine 100 mg Tablets. Center: Taro Generic Lamotrigine 100 mg Tablets. Right: Dr. Reddy Generic Lamotrigine 100 mg Tablets.
Lamictal also comes in liquid capsules, but those aren’t available in the US.
Other Trade Names and Overseas Availability
Not including controlled/extended/sustained release suffixes (Efexor ER, Trevilor retard e.g.) or branded generics that are a hyphenate of the generic name and the drug company name (Apo-Citalopram e.g.).
Available as Lamictal in These Countries
- New Zealand
Available as Generic Lamotrigine in These Countries
- New Zealand
- South Africa
Transliterated, Overseas Trade and Branded Generic Names
- Amitral: Algeria
- Crisomet: Spain
- Labileno: Spain
- Loxol: Iraq, Jordon, Saudi Arabia
- لاميكتال: Algeria, Egypt, Saudi Arabia - “Lamictal” transliterated into Arabic
- لامكتال: Jordon
- أميترال: Algeria
- لوكسول: Saudi Arabia
- 라믹탈: Korea
- Ламиктал: Russia - “Lamictal” transliterated into Cyrillic
- למיקטל: Israel - “Lamictal” transliterated into Hebrew
- Lamictin: South Africa
- Lamitor: South Africa
- lamotrigin: Austria, Czech Republic, Denmark, Finland, Germany, Norway, Sweden, Switzerland
- lamótrigín: Iceland
- lamotrigina: Argentina, Brazil, Chile, Italy, Mexico, Peru, Portugal, Spain, and probably everywhere else they speak Italian, Portuguese, or Spanish
- Lamotrine: Egypt, Yemen
- למוג’ין: Israel - “lamotrigine” transliterated into Hebrew
Full US PI sheet, Global SPCs & PILs, Other Consumer Review & Rating Sites, and Other Sites that may be of Interest
Lamictal’s Full US Prescribing Information / PI Sheet
PI Sheets for Other Forms
PI Sheets from Around the World
Rating & Review Sites
Other Sites of Interest
If you have any questions not answered here, please see the Crazymeds Lamictal discussion board.
- the Full US Lamictal PI sheet
- Faught, Edward. “Topiramate in the treatment of partial and generalized epilepsy.” Neuropsychiatric disease and treatment 3.6 (2007): 811-821.
- Stahl, Stephen M. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Third edition Cambridge University Press 2008. ISBN:978–0521673761
- Julien, Robert M. Ph.D, Claire D. Advokat, and Joseph Comaty Primer of Drug Action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs 12th edition Worth Publishers 2011. ISBN:978–1429233439
- Stahl, Stephen M. The Prescriber’s Guide (Essential Psychopharmacology Series) Third edition Cambridge University Press 2009. ISBN:978–0521743990
- Virani, Adil S., K. Bezchlibnyk-Butler, and J. Jeffries Clinical Handbook of Psychotropic Drugs 18th edition Hogrefe & Huber Publishers 2009. ISBN:978–0889373693
- Silberstein, Stephen D., Michael J. Marmura Essential Neuropharmacology: The Prescriber’s Guide Cambridge University Press 2010. ISBN:978–0521136723
- Stein, Dan, Bernard Lerer, Stephen Stahl Evidence-based Psychopharmacology Cambridge University Press 2005. ISBN:978–0521531887
- Kaufman, David Myland, MD Clinical Neurology for Psychiatrists W.B. Saunders Company 2001 ISBN:1416030743
- Levy, René H., Richard H. Mattson, Brian S. Meldrum, and Emilio PeruccaAntiepileptic Drugs Lippincott Williams & Wilkins 2003. ISBN:0781723213
- Mosby’s Drug Consult 2007 (Generic Prescription Physician’s Reference Book Series) © 2007 ISBN:978-0323040587 An imprint of Elsevier.
- PDR: Physicians’ Desk Reference 2010 64th edition
- Marson, Anthony G., Asya M. Al-Kharusi, Muna Alwaidh, Richard Appleton, Gus A. Baker, David W. Chadwick, Celia Cramp et al. “The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial.” The Lancet 369, no. 9566 (2007): 1000-1015.
- Marson, Anthony G., Asya M. Al-Kharusi, Muna Alwaidh, Richard Appleton, Gus A. Baker, David W. Chadwick, Celia Cramp et al. “The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.” The Lancet 369, no. 9566 (2007): 1016-1026.
- Arif, Hiba, Richard Buchsbaum, Joanna Pierro, Michael Whalen, Jessica Sims, Stanley R. Resor, Carl W. Bazil, and Lawrence J. Hirsch. “Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.” Archives of neurology 67, no. 4 (2010): 408-415.
- Fuller, Matthew A. “Medical Management of Bipolar Disorder: A Pharmacologic Perspective.” ANNALS OF CLINICAL PSYCHIATRY (2011): 23-48.
- “Lamictal (lamotrigine) and Lamisil (terbinafine hydrochloride) ‘Dear Healthcare Professional Letter.’” U.S. Food and Drug Administration website. 2000 Last Updated: 08/03/2009. Last Accessed: 17 July 2014.
- Hikma Pharmaceuticals Central Nervous System Portfolio Last Accessed 04 July 2014
- ChemSpider’s lamotrigine page Last Accessed 04 July 2014
- New Zealand Medicines and Medical Devices Safety Authority Medicine Data Sheet for Lamictal Dispersible/Chewable Tablets Last Accessed 04 July 2014
- electronic Medicines Compendium Summary of Product Characteristics for Lamictal Tablets SPC Last updated 08 April 2014. Last Accessed 04 July 2014
‹< Lamictal’s Pharmacology |
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|Last modified on Wed, 04 May, 2016 at 17:22:00 by JerodPoore||Page Author Jerod Poore||Date created January 18, 2011, at 15:16:23|
|“Lamictal (lamotrigine): Availability, Comments, Links, More” by Jerod Poore is copyright © 2011 Jerod Poore ||Published online 2011/01/18|
Lamictal, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Lamictal’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.
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Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.
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