how long until Geodon starts to work, likelihood Geodon will work for your condition, and Geodon vs. other Antipsychotics

> How Long Until Geodon Works

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Approved & Off-label Uses | Geodon Index | How to Take and Discontinue
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Comparatively Effective

Two of the most important things to know when deciding on which med is the best for a particular condition1: how likely is it to work and how long will it take.

The odds of a med working for a particular condition and how long it generally takes to work should be fairly easy to nail down, and not need to be summed up by the Internet shorthand YMMV (Your Mileage May Vary). Aside from it being hard enough to get an accurate diagnosis when brain cooties are involved, why is it so difficult to figure out if Geodon (ziprasidone) is right for you and how long it will take for you to know that?

  • Because no one is quite sure exactly what causes various conditions.
  • Which is further complicated when everything is a spectrum disorder (e.g. bipolar 1, bipolar 2, all the others they still ignored in DSM-5).
  • And they’re never really sure about how Geodon works in the first place.
  • Plus, if you have more than one condition for which you’re taking one or more medications to treat, things get really complicated.
  • None of which is helped by studies that produce contradictory results and other quirks in The Literature.

Always remember: if your symptoms suddenly get a lot worse, call your doctor immediately. Any drug that makes your symptoms worse is a drug you probably need to stop taking as soon as possible.

We reference a shitload of studies here, so you might want to see our pages on how to deal if a study is legitimate and the tests and methodologies researchers use to measure the efficacy of medications, including during clinical trials to get FDA approval.

How Long Until Geodon (ziprasidone) Starts Working

Like most APs Geodon works quickly. While IM Geodon may not be as fast as Relprevv (IM Zyprexa) in an ER setting, if you don’t get noticeable positive benefit within three days it’s time to move on to another AP.

How Effective Geodon (ziprasidone) is for its Approved Uses

I’ll get back to you on how well Geodon / Zeldox (ziprasidone) works in the real world. For now let’s see how things look in the literature.

Bipolar Disorder

  • Ziprasidone in the treatment of mania in bipolar disorder. You know a drug company is confident in its product when it makes the clinical trials it used for the FDA approval available for free on Pub Med Central. With a shitload of data. Of course the paper is spun to make Geodon look especially good, the trials being sponsored by Pfizer and all, but a lot of the ugly stats are presented without sugar coating. Stats like 90% of people getting Geodon in one trial had side effects of some kind (compared with 77%(!) getting the placebo), although only 6% of those who took Geodon dropped out due to side effects. Still, almost half of the people who took Geodon dropped out of one trial and 40% quit the other. Only half the people taking Geodon had a 50% or better reduction in symptoms in the first study, but it was just 46% in the second. That barely qualifies as a functional med to the FDA. As for being an add-on to lithium, what the hell does this mean: [A]ugmentation with ziprasidone helped provide rapid reduction of manic symptoms and greater improvement in overall psychopathology, although symptoms of mania were not significantly decreased by ziprasidone augmentation. Buh? How can a med reduce manic symptoms without decreasing symptoms of mania? That’s like all those people with bipolar disorder who say they feel great when taking lithium orotate. Of course they feel great, they’re manic as fuck! So….
  • The role of ziprasidone in adjunctive use with lithium or valproate in maintenance treatment of bipolar disorder. If your first clinical trial fails, do another one. The FDA allowed them to do what looks like a single-blind study, where the patients didn’t know if they were getting a placebo or Geodon with their lithium or valproate, but the researchers did. A chunk of the paper includes Pfizer’s whining about how clinical trials are conducted. Geodon worked a lot better this time.
  • Does Geodon/Zeldox work better for Bipolar if you’re fat? I’m not so sure about this study. I don’t think Geodon works better for the obese so much as anyone who is overweight and taking several meds is going to be willing to put up with a one med’s side effects over another’s. I’m not surprised over a quarter of them were clinically really happy in a non-manic way (euthymia) after losing 21 pounds:

Moreover, obese compared to nonobese patients had a higher rate of shift to final-visit euthymia (27.5% vs 0.0%, P = 0.0002), and more weight loss (−20.7 lbs vs −0.6 lbs, P = 0.001) Enhanced Ziprasidone Combination Therapy Effectiveness in Obese Compared to Nonobese Patients With Bipolar Disorder

Likelihood Geodon (ziprasidone) will Work for Off-Label Applications

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Geodon (ziprasidone) versus Other Antipsychotics for its Approved Indications

How Geodon (ziprasidone) Compares with Other Drugs for Off-Label Treatments

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Approved & Off-label Uses | Geodon Index | How to Take and Discontinue

1 Assuming you were correctly diagnosed in the first place.

If you have any questions not answered here, please see the Crazymeds Geodon discussion board. We welcome criticisms of the articles, notifications of bad links, site problems, consumer experiences with medications, etc. I’m not always able to write back. Hence I never answer questions about meds via e-mail that are answered by this or other articles. Especially if they have been repeatedly asked on the forum. That’s why we write these damn things. Questions about which meds are best for your condition should also be asked on the forum; because this is a free site, so the price of admission is making things easier for somebody else searching for the same answer. We don’t deal with children on the forum or in private because after doing this for ten years I don’t have the emotional stamina to deal with kids who have brain cooties. How to contact Crazymeds. — Jerod Poore, CME, Publisher Crazymeds (

Last modified on Tuesday, 24 September, 2013 at 18:13:28 by JerodPoorePage Author Date created Friday, 28 December 2012 at 12:49:43
“Geodon (ziprasidone): a Review for the Educated Consumer.” by Jerod Poore is copyright © 2012 Jerod Poore Published online 2012/12/29
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Geodon, and all other drug names on this page and used throughout the site, are a trademark of someone else. Geodon’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

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All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
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Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained from the medications’ product information / summary of product characteristic (PI/SPC) sheets and/or medication guides - which is all you get from sites like WebMD, RxList, NAMBLA NAMI, etc., the sources that are referenced throughout the site, our personal experience and the experiences family, friends, and what people have reported on various reputable sites all over teh intergoogles. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or medication guide/patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Very little information about visitors to this site is collected or saved. From time to time I look at search terms used and which pages they bring up in an effort to make the information I present more relevant. And the country of origin, just because I’m geeky like that. That’s about it. Depending on how you feel about Schrodinger, our privacy policy should either assuage or exacerbate your paranoia.
Crazymeds is optimized for ridiculously large screens and browsers that don’t block ads. I use Firefox and Chrome, running under Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
Crazymeds now uses a secure server, but it is not so secure that you can discuss anything having to do with nuclear power facilities, air traffic control systems, aircraft navigation systems, weapons control systems, or any other system requiring failsafe operation whose failure could lead to injury, death or environmental damage. Just so you know. So if you’re mentally interesting and have a job that deals with that sort of thing, talk about said job elsewhere. Otherwise feel free to discuss your meds and brain cooties.
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1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.

3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas?* I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion as anonymity on teh Intergoogles. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.

* Yes, I know I’m using open source browsers. I also test the site using the now-defunct IE and Safari browsers. Their popularity - and superiority - killed IE and Safari, so that’s why I rely on the open source browsers. It’s like brand vs. generic meds. Sometimes the generic is better than the brand.

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