Highlighting uses, dosage, how to take and discontinue


Fetzima’s Side Effects, Warnings, etc. >>

Brand & Generic Names; Drug Classes

US brand name: Fetzima
Generic name: levomilnacipran extended-release

Drug Class(es)

Primary drug class: Antidepressants
Additional drug class(es): Serotonin and Norepinephrine Reuptake Inhibitors

Approved & Off-Label Uses (Indications)

Fetzima’s US FDA Approved Treatment(s)

short-term (8 weeks) treatment of Major Depressive Disorder (MDD).

Uses Approved Overseas but not in the US

Off-Label Uses of Fetzima

I have never seen this before:

Limitation of Use: FETZIMA is not approved for the management of fibromyalgia. The efficacy and safety of FETZIMA for the management of fibromyalgia have not been established. --the Fetzima PI sheet

Forest is specifically telling doctors and consumers to not use a med for an off-label purpose. While Forest has a vested interest in making sure people still buy Savella, based upon how Fetzima works, they do have a point. Fetzima isn’t going to make you puke like Savella, and it’s easier to take, but it won’t work as well for fibromyalgia or other forms of chronic pain than Savella will. BUT, a med you can tolerate that does a half-assed job is better than a med you literally can’t stomach. So if Savella works better for you than Cymbalta, but you can’t deal with the side effects, you may as well give Fetzima a shot. Just make sure the side effects weren’t from SSRI/SNRI discontinuation syndrome. If you were taking 60mg (or more) a day of Cymbalta and your doctor had you stop taking it all at once when starting you at 12.5 mg of Savella, find another doctor! Then consider giving Savella another chance.

When & If Fetzima Will Work

Fetzima’s Usual Onset of Action (when it starts working)

Like any SNRI, expect Fetzima to start working in 2 to 4 weeks.

Likelihood of Working

Fetzima doesn’t seem to be much better than most antidepressants in the short-run. When it comes to long-term (maintenance) use,Fetzima is only so-so when it comes to keeping depression away.

Taking and Discontinuing

How to Take Fetzima

Manufacturer’s Recommendations

Forest Laboratories recommends:

The recommended dose range for FETZIMA is 40 mg to 120 mg once daily, with or without food. FETZIMA should be initiated at 20 mg once daily for 2 days and then increased to 40 mg once daily. Based on efficacy and tolerability, FETZIMA may then be increased in increments of 40 mg at intervals of 2 or more days. The maximum recommended dose is 120 mg once daily.

FETZIMA should be taken at approximately the same time each day. FETZIMA should be swallowed whole. Do not open, chew or crush the capsule.

 --the Fetzima PI sheet

Crazymeds’ Suggestions

How to Stop Taking Fetzima (discontinuation / withdrawal)

It’s an SNRI, so you had better do it as slowly and carefully as possible.

Keep Crazymeds on the air.
Donate some spare electronic currency
you have floating around The Cloud

Fetzima’s Side Effects, Warnings, etc. >>

Pages and Forum Topics Google Thinks are Relevant to Your Mental Health

Last modified on Wed, 04 May, 2016 at 17:16:50 by JerodPoorePage Author Date created Wed, 08 Oct, 2014
“Fetzima (levomilnacipran extended-release): Uses and Using” by Jerod Poore is copyright © 2014 Jerod Poore Published online 2014/10/08

Fetzima, and all other drug names on this page and used throughout the site, are the trademarks of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

Page design and explanatory material by Jerod Poore, copyright © 2003 - 2016. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.

Enable Crazymeds’ Financial Solvency!

Enable Crazymeds to keep spreading our knowledge. Donate some spare e-currency you have floating around The Cloud.

Improve Your Social Media Skills


Follow our Highly Irregular Updates and Paranoid Rants Other News


Square this Circle

For Site News and NeuroPsych Research


Show us teh like™

Crazymeds: The Blog

For Site News and Crap that Distracts me from my Fucked-up Life

Crazymeds’ Tumblr

Mentally Interesting Advocacy

OpEd News

Daily Kos

Sites That Probably Suck Less Than Crazymeds

Crazymeds Merchandise

Available at Straitjacket T-Shirts

Vaccines Cause Immunity bumpersticker at Straitjacket T-Shirts

Stuck Up
All stickers $5. Now Available in Packs of 10 & 50

Mentally Interesting button at Straitjacket T-Shirts

Button It!
2.25″ $4 & 3.5″ $4.50. Now Available in Packs of 10 & 100