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‹< Effexor’s Pharmacology |

US brand name: Effexor
Generic name: venlafaxine

Comments

There are two last resorts among the modern, first-line meds to cure the deepest, blackest depression when your doctor is just switching you from one horsie to another on the med-go-round: Effexor and Remeron (mirtazapine)1. Either in combination with an antipsychotic, especially Geodon would really get you out of that hole of despair, but first you should throw away every mirror and scale in your house and buy expandable clothing. Weight gain usually isn’t too bad with Effexor alone, but when coupled with Remeron and/or most antipsychotics…well…prepare yourself for being a jolly fatty.

Effexor has to be the. most. loathed. drug by those for whom it didn’t work. While it can be an absolute lifesaver for many people with the most severe form of whaleshit-on-the-bottom-of-the-ocean depression, with or without anxiety, as well as for those with various forms of anxiety without depression, when it doesn’t work well enough, and the side effects suck to much, the discontinuation syndrome can be such a nightmare that people will fire their doctors who didn’t work out a discontinuation schedule or otherwise prepare them for what it would be like.

A couple things I’ve picked up from the plethora of overseas SPCs and PILs I’ve collected (see below)

  • In Australia they’ve noticed “an increased risk of bone fractures in patients receiving serotonin reuptake inhibitors (SRIs) including venlafaxine.”
    • There’s nothing explicit about that in the US PI sheet, just a mention of osteoporosis as a rare side effect.
  • Effexor is effective in treating depression in Parkinson’s Disorder, and that’s a very popular off-label use in east Asia.
    • I can’t think of anyone more susceptible to bone fractures than old Asian women with Parkinson’s. Except for someone with osteogenesis imperfecta.
  • I have no idea if the bone fracturing susceptibility from SSRIs and SNRIs is something that happens only to Australians, but it definitely happens with older adults no matter where they live, so if Grandma is taking Effexor or any other serotonergic drug, she needs to be even more careful about falling down and not being able to get up.

Name, Address, Serial Number (Generic and Overseas Availability)

Available in the US as a generic? Yes

Shapes & Sizes (How Supplied)

Extended-release capsules ; Immediate-release, shield-shaped tablets

Effexor XR capsule and Effexor tablets
From left: Effexor XR 37.5 mg, Effexor 75 mg, Effexor 25 mg
 


Other Trade Names and Overseas Availability

Not including controlled/extended/sustained release suffixes (Efexor ER, Trevilor retard e.g.) or branded generics that are a hyphenate of the generic name and the drug company name (Apo-Citalopram e.g.).

Available as Effexor in

  • Algeria (إفإكسور in Arabic)
  • Bulgaria
  • Canada
  • France
  • Morocco
  • Tunisia

Overseas Trade and Branded Generic Names

In addition to being available as a generic under the local INN (see below), Effexor is available in these countries under the following trade and branded generic names:

  • Algeria / الجزائر - Flaxyne / فلاكسين , Venexor / فينيكسور
  • Argentina - Alfaxin , Efexor , Elafax , Ganafax , Mezine , Pramina , Quilarex , Sesaren , Sunvex , Venlifax
  • Armenia / Հայաստան - Efevelon / Էֆեվելոն
  • Australia - Altven , Efexor, Elaxine , Enlafax
  • Austria / Österreich - Efectin , Faxiprol , Venaxabene , Venlafab
  • Bahrain - Efexor
  • Belarus / Беларусь - Alventa / Алвента , Deprexor / Депрексор , Efevelon, Velaxin / Велаксин
  • Belgium / België / Belgique - Efexor, Venlax
  • Bolivia - Elafax, Nervix , Oprax , Sesaren, Venlax
  • Bosnia & Herzegovina / Bosna i Hercegovina - Alventa, Depressa , Efexiva 2, Velafax , Venlax, Zanfexa
  • Brazil - Alenthus ,Efexor, Venlaxin , Venlaxina , Venlift
  • Bulgaria / България - Alventa / Алвента, Argofan / Аргофан , Deprexor / Депрексор, Efectin / Ефектин , Efevelon / Эфевелон , Efexiva / Ефексива , Elify / Елифай , Estaq / Естак , Lanvexin / Ланвексин , Laroxin / Лароксин , Nopekar / Нопекар , Prefaxin / Префаксин , Tifaxin / Тифаксин , Velaxin / Велаксин, Venlagamma / Венлагамма , Venlift / Венлифт ,
  • Chile - Axone , Depurol , Ectien , Efexor, Elafax, Lafaxin , Nervix, Nezel , Norpilen , Senexon , Sentidol , Sesaren, Subelan , Vencontrol , Venlax
  • China / 中国 - Efexor / 怡諾思
  • Colombia - Desmaril , Eduxon , Efexor, Exer , Hanxinex , Leire , Mezine, Niztec , Norpilen, Procaps , Sesaren, Vencontrol, Vendep , Veniz , Venlax, Venoxor , Vilfax
  • Costa Rica - Efexor, Neurosenexon , Sesaren
  • Croatia / Hrvatska - Alventa, Efexiva, Velafax, Velfax , Vexin , Zanfexa
  • Cyprus - Efexor
  • Czech Republic / Česká republika - Argofan, Efectin, Elify, Faxiprol, Mollome , Olwexya , Tifaxin, Velaxin
  • Denmark - Dobupal , Efexor, Vandral
  • Dominican Republic / República Dominicana - Efexor, Elafax, Lafaxin, Valax , Venfane
  • Ecuador - Ansifix , Efexor, Valax, Sesaren, Venlax
  • Egypt / مصر - Delvena , Efexor / إفإكسور , Effegad , Effoxbelle , Idixor , Venlatrin , Venlaxine , Vexamod
  • El Salvador - Efexor
  • Estonia / Eesti - Alventa, Argofan, Efexor, Faxiv , Lanvexin, Sulinex , Venegis , Venib , Venladep , Venlagamma, Vessril
  • Finland / Suomi - Akaven , Alventa, Efexor, Faxoven , Ofaven , Velassine , Venlafarm , Venlar , Venlasan , Vexipress
  • France - Trevilor
  • Georgia / საქართველო - Velaxin, Venlagamma, Venlaxor
  • Germany / Deutschland - Lindalex , Trevilor, Venla ,Venlagamma, Venla-q Venlasan
  • Greece / Ελλάδα - Argofan, Arvifax , Deprevix , Efaxin , Efetrin , Efexor, Elify, Melocin , Memomax , Norafexine , Norezor , Serosmine , Tudor , Velept , Velpine , Venaxol , Ven-Fax , Venfaxil , Venlasan, Venlaxin, Voxafen , Zacalen , Zaredrop
  • Guatemala - Bonilux , Efexor, Limbic , Mezine, Neurosenexon, Sesaren, Sinasfix , Venlacross , Veslodat
  • Honduras - Efexor
  • Hong Kong / 香港 - Efexor / 怡諾思
  • Hungary / Magyarország - Efectin, Falven , Faxiprol, Jarvis , Olwexya, Venlagamma, Venlaxin
  • Iceland - Efexor
  • India / भारत - Dalium , Envelaf , Flavix , Sentosa , Velaf , Velfex , Velax , Ven OD , Venaxin , Venish , Venlamax , Venlor , Venset , Ventab , Vendep, Veniz, Venjoy , Venla, Venlift, Venx , Vexor , VNF
  • Indonesia - Efexor
  • Iran / ایران - Alventa, Depraxin , Deprilax , Venlabiox , Venlaxin
  • Ireland / Éire - Efaxil , Efexor, Tonpular , Vedixal , Velexor , Venex , Venlablue , Venlift, Venlofex
  • Israel / ישראל - Efexor / אפקסור, ViePax
  • Italy - Efexor, Faxine , Tifaxin, Zaredrop, Zarelis
  • Jordan / الأردن - Vaxor , Venexor / فينيكسور
  • Kazakhstan / Казахстан - Alventa / Алвента, Efevelon / Эфевелон, Prefaxin / Префаксин, Velaxin / Велаксин
  • Kenya - Veniz
  • Latvia - Alventa, Argofan, Efexor, Elify, Prefaxine , Velaxin, Venlaxor
  • Lebanon / لبنان - Defaxine / ديفاكسين , Efexor / إفإكسور , Venlax / فينلاكس
  • Lithuania / Lietuva - Alventa, Efexor, Elify, Lanvexin, Velaxin
  • Macedonia (FYROM) /македонија - Alventa / Алвента, Efexiva / Ефектин, Velafax, Velahibin , Venlax, Zanfexa
  • Malaysia - Efexor
  • Malta - Efexor
  • Mexico - Adefaxin , Benolaxe , Efexor, Lafaxven , Mazda 3, Odven , Vextor
  • Myanmar (Burma) - Venlift
  • Netherlands - Efexor, Venfalex , Venladoz , Venlatif , Venlexor
  • New Zealand - Efexor
  • Nicaragua - Efexor
  • Norway / Norge - Efexor
  • Oman / عمان - Efexor / إفإكسور ,
  • Pakistan / پاکستان - Amfax , Efexor, Enpress , Intefred , Peofax , Vanaxin , Vela , Venalax 4, Venice , Venxor , Vinoxa
  • Panama - Efexor
  • Paraguay - Elafax, Neoxacina , Sesaren,
  • Peru - Anapresin , Asegur , Depurol , Efexor, Elafax, Noviser , Senexon, Vafexin , Veniz, Vfax
  • Philippines - Efexor
  • Poland / Polska - Alventa, Axyven , Efectin, Efevelon, Efexiva, Faxigen , Faxolet , Jarvis, Lafactin , Lanvexin, Nopekar, Oriven , Prefaxine, Symfaxin , Tavex , Tifaxin, Tonpular, Velfax, Velaxin, Velaxiran 5, VenaLEK , Venlabax , Venlagamma, Venlax, Venlectine , Zaredrop
  • Portugal - Bitural , Desinax , Efexor, Efique , Genexin , Leritex , Pracet , Venxin , Xapnev , Zaredrop, Zarelix
  • Romania - Adoxa , Alventa, Argofan, Efectin, Elify, Fobiless , Ivryx , Jarvis, Nopekar, Posipres , Velaxin, Venlagamma
  • Russia / Россия - Alventa / Алвента, Efevelon / Эфевелон, Prefaxin / Префаксин, Velaxin / Велаксин
  • Saudi Arabia / العربية السعودية - Efexor / إفإكسور , Venaxine , Venex , Vexal
  • Serbia / Србија - Velafax
  • Singapore / 新加坡 - Efexor, ViePax
  • Slovakia / Slovensko - Alventa,
  • Slovenia - Alventa, Efectin, Efexiva, Faxiprol, Nefexyl , Venlagamma
  • South Korea / 남쪽 한국 - Cofexor / 코팩사 , Depron / 데프론 , Efexor / 이팩사 , Ivencine 6 / 이벤신 , Lavensa 7 / 라벤사 , Prexa / 프렉사 , Venexor / 베넥사 , Venfaxin / 벤팍신오알 , Venlafact / 벤라팩트 , Vivafaxine / 비바팍신 , 베라칸­
  • Spain / España - Arafaxina , Conervin , Dislaven , Dobupal, Flaxen 8, Levest , Vandral, Venlabrain , Venlamylan , Venlapine , Zaredrop, Zarelis
  • Sweden / Sverige - Durnit , Efexor, Trevilor, Venette , Venlanidda , Venlix
  • Switzerland / Suisse / Schweiz / Svizzera - Efexor, Venlax
  • Taiwan / 台灣 - Calmdown 9, Easyfor , Efexor / 怡諾思, Faxine, Rafax , Seroxine , Valosine , Venfaxime , Venforspine
  • Tanzania - Venexor, Venlift
  • Thailand / ประเทศไทย - Efexor
  • Turkey / Türkiye - Efexor, Sulinex, Venegis, Venfecto , Vessril
  • UAE / الإمارات العربية المتحدة - Efexor /إفإكسور , Venlax / فينلاكس
  • UK - Depefex , Efexor, Foraven , Politid , Sunveniz , Tonpular, Venaxx , Venladex , Venlalic , ViePax, Winfex
  • Uganda - Venexor, Venlift
  • Ukraine / Україна - Alventa / Алвента, Deprexor / Депрексор, Efevelon / Эфевелон, Faxine, Prefaxin / Префаксин, Velaxin / Велаксин,
  • Uruguay - Elafax, Limbic, Nulev , Venxine
  • Venezuela - Efexor, Idoxen , Lafaxim , Sesaren, Velmed
  • Việt Nam - Venlift

Alternate INNs

because you can’t eat just one
  • venlafaksin - Bosnian, Croatian, Norwegian, Serbian, Slovenian, Turkish
  • venlafaksiin - Estonian
  • venlafaksiini - Finnish
  • venlafaxin - German, Swedish, Vietnamese
  • venlafaxina - Italian, Portuguese, Spanish
  • venlafaxinum 10 - Latin
  • venlafaksino - Lithuanian
  • venlafaxină - Romanian
  • الفينلافاكسين Arabic transliteration of venlafaxine
  • 文拉法辛 Chinese transliteration of venlafaxine
  • венлафаксин Cyrillic transliteration of venlafaxine
  • Βενλαφαξίνη Greek transliteration of Venlafaxine
  • ונלפאקסין Hebrew transliteration of venlafaxine
  • 벤라팍신 Korean transliteration of venlafaxine

Full US PI sheet, Global SPCs & PILs, Other Consumer Review & Rating Sites, and Other Sites that may be of Interest

Effexor’s Full US Prescribing Information / PI Sheet

Prescribing Information and Patient Information from Around the World

PI = Prescribing Information PIL = Patient Information Leaflet PM = Product Monograph SPC = Summary of Product Characteristics CMI = Consumer Medicine/Medical Information MDS = Medicine Data Sheet EPAR = European Public Assessment Reports
See the page on how to read our drug guides for detailed translations and explanations of these and other prescribing information-related initialisms & acronyms.

Other Review Sites

Other Sites of Interest



Discussion board

If you have any questions not answered here, please see the Crazymeds Effexor discussion board.

References

  1. Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. The British Journal of Psychiatry (2006) 189:124-131 R. M. Post, MD; L. L. Altshuler, MD; G. S. Leverich, MSW; M. A. Frye, MD; W. A. Nolen, MD; R. W. Kupka, MD, PhD; T. Suppes, MD; S. McElroy, MD and P. E. Keck, MD; K. D. Denicoff, MD; H. Grunze, MD; J. Walden, MD; C. M. R. Kitchen, PhD; J. Mintz, PhD
  2. Antidepressants in Bipolar Disorder: No Benefit, Possible Harm medscape.com May 30, 2013 Caroline Cassels
  3. Randomized, Double-Blind, Placebo-Controlled Crossover Trials of Venlafaxine for Hot Flashes After Breast Cancer The Oncologist January 2007 vol. 12 no. 1 124-135 Janet S. Carpenter, Anna Maria Storniolo, Shelley Johns, Patrick O. Monahan, Faouzi Azzouz, Julie L. Elam, Cynthia S. Johnson and Richard C. Shelton
  4. Prophylaxis of migraine: open study with venlafaxine in 42 patients Arq. Neuro-Psiquiatr. vol.56 n.4 São Paulo Dec. 1998 Dr. Estevão Demétrio Nascimento
  5. Venlafaxine versus amitriptyline in the prophylactic treatment of migraine: randomized, double-blind, crossover study Clinical Neurology and Neurosurgery 107 (2004) 44–48 Serpil Bulut, M. Said Berilgen, Aslihan Baran, Aslan Tekatas, Murad Atmaca, Bulent Mungen
  6. Modification of morphine analgesia by venlafaxine in diabetic neuropathic pain model. Pharmacological Reports 2012, 64, 1267–-1275 Cegielska-Perun K, Bujalska-Zadrożny M, Makulska-Nowak HE.
  7. Efficacy and tolerability of venlafaxine extended release in patients with major depressive disorder. Psychiatria Danubina, 2010; Vol. 22, No. 3, pp 413–417 Plesničar BK
  8. Assessing Rates and Predictors of Tachyphylaxis During the Prevention of Recurrent Episodes of Depression With Venlafaxine ER for Two Years (PREVENT) Study. Psychopharmacol Bull. 2009; 42(3): 5–20. Dr. Anthony J. Rothschild, MD, Dr. Boadie W. Dunlop, MD, Dr. David L. Dunner, MD, Dr. Edward S. Friedman, MD, Dr. Alan Gelenberg, MD, Dr. Peter Holland, MD, Dr. James H. Kocsis, MD, Dr. Susan G. Kornstein, MD, Dr. Richard Shelton, MD, Dr. Madhukar H. Trivedi, MD, Dr. John M. Zajecka, MD, Dr. Corey Goldstein, MD, Dr. Michael E. Thase, MD, Dr. Ron Pedersen, MD, and Dr. Martin B. Keller, MD
  9. Psychopharmacology Research Tutorial for Practitioners - Antidepressant Drugs: Is a Dual Mechanism Better? Primary Psychiatry 2004;11(8):17-18 Donald S. Robinson, MD
  10. Stahl, Stephen M. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Third edition Cambridge University Press 2008. ISBN:978–0521673761
  11. Julien, Robert M. Ph.D, Claire D. Advokat, and Joseph Comaty Primer of Drug Action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs 12th edition Worth Publishers 2011. ISBN:978–1429233439
  12. Diamond, Ronald J., MD Instant Psychopharmacology 2nd Edition W.W. Norton 2002. ISBN:978–0393703917
  13. Drummond, Edward, MD The Complete Guide to Psychiatric Drugs John Wiley & Sons 2000. ISBN:0471353701
  14. Effexor Prescribing Information
  15. Mosby’s Drug Consult 2007 (Generic Prescription Physician’s Reference Book Series) © 2007 An imprint of Elsevier.
  16. PDR: Physicians’ Desk Reference 2010 64th edition
  17. Healing Anxiety & Depression Daniel G. Amen, M.D., and Lisa C. Routh, M.D. © 2003. Published by G.P. Putnam’s Sons.
  18. Dutch Patient Information Leaflet. Last retrieved 07 November 2014

‹< Effexor’s Pharmacology |

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1 Stahl will combine it with Remeron - a cocktail he calls "California Rocket Fuel" - for his patients who are truly, and dangerously alt.depressed.as.fuck, and who have not responded to anything else.

2 I love how this translates to "Possibly effective."

3 As with Celica in Australia, I don't know how a drug company can, or why they would name one of their products after a car.

4 Doesn't Venalax, or anything ending with "alax" sound like a laxative? Given how SNRIs are much more likely to cause constipation than diarrhea that's another example of ironic branding.

5 Ironically, not a trade name in Iran.

6 Google translates this name to "Renal events." I guess anyone with kidney problems should avoid this one.

7 Translates to "raven", so they must be going after whatever the Korean equivalent to Goth is.

8 This one must be specifically for people with blonde hair.

9 Well, it is approved to treat anxiety.

10 I've also seen venlafaxini hydrochloridum as the active ingredient of some central- and eastern-European generics. I don't know enough (i.e. anything) about Latin to know if that is even correct usage or not. Let alone if venlafaxinum is correct. Latin generic names are all bullshit as far as I'm concerned.


Last modified on Wed, 04 May, 2016 at 17:11:29 by JerodPoorePage Author Date created Monday, 25 April, 2011 at 11:53:36
“Effexor (venlafaxine): Availability, Comments, Links, More” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/04/25

Effexor, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Effexor’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



Page design and explanatory material by Jerod Poore, copyright © 2003 - 2016. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.

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