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« Cymbalta’s Side Effects, Warnings, etc. | Cymbalta’s Pharmacology »

US brand name: Cymbalta
Generic name: duloxetine

Cymbalta’s Pros and Cons

Pros

Works quickly with a fairly low side effect profile for an SNRI. Less likely to poop-out than an SSRI. Probably the best painkiller around as far as approved antidepressants are concerned (because Savella (milnacipran) is not approved in the US as an antidepressant).



Cons

It’s an SNRI, which means a discontinuation syndrome from hell if you want/need to stop taking it.

Interesting Stuff your Doctor Probably didn’t Tell You about Cymbalta

Cymbalta is more effective when taken in the morning than in the evening. This has nothing to do with meals, it all has to do with our circadian rhythms.

Smoking decreases Cymbalta’s bioavailability by about one-third. Eli Lilly doesn’t recommend any changes to how much you take or how fast to increase the dosage if you smoke, but don’t be surprised if you need to take more sooner than you thought.

Best Known for

Not that much these days. It’s either the med approved for a much stuff as Prozac or Paxil, or the drug that makes you feel better enough to not celebrate with any alcohol because your liver could explode if you do.




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« Cymbalta’s Side Effects, Warnings, etc. | Cymbalta’s Pharmacology »

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Last modified on Wed, 04 May, 2016 at 17:03:03 by JerodPoorePage Author Date created April 05, 2011, at 15:24:23
“Cymbalta (duloxetine): Pros and Cons” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/04/05

Cymbalta, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Cymbalta’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

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