|US brand name: Cymbalta|
|Generic name: duloxetine|
Cymbalta’s Pros and Cons
Works quickly with a fairly low side effect profile for an SNRI. Less likely to poop-out than an SSRI. Probably the best painkiller around as far as approved antidepressants are concerned (because Savella (milnacipran) is not approved in the US as an antidepressant).
It’s an SNRI, which means a discontinuation syndrome from hell if you want/need to stop taking it.
Interesting Stuff your Doctor Probably didn’t Tell You about Cymbalta
Cymbalta is more effective when taken in the morning than in the evening. This has nothing to do with meals, it all has to do with our circadian rhythms.
Smoking decreases Cymbalta’s bioavailability by about one-third. Eli Lilly doesn’t recommend any changes to how much you take or how fast to increase the dosage if you smoke, but don’t be surprised if you need to take more sooner than you thought.
Best Known for
Not that much these days. It’s either the med approved for a much stuff as Prozac or Paxil, or the drug that makes you feel better enough to not celebrate with any alcohol because your liver could explode if you do.