« Brintellix’s Side Effects, Warnings, etc. | Brintellix’s Pharmacology »

US brand name: Brintellix
Generic name: vortioxetine

Brintellix’s Pros and Cons


  • It’s like Viibryd on steroids, but even more targeted. So if serotonin is your friend, Brintellix could be your bestest friend ever.
  • Discontinuation symptoms can range from mild to non-existent for most people.
  • Super-low side effect profile.
  • Easy titration.


  • It’s like Viibryd on steroids, so if serotonin turns out to be your worst enemy Brintellix could be a bit of a nightmare.
  • All the things that make for little to no discontinuation syndrome? Yeah, that just means any unpleasant effects you have from too much serotonin will stick around for at least a week. Maybe two.
  • Anything with a really low side effect profile tends to have something where it’s the worst of any med, or at least crazy med, on the planet. Like Keppra’s suicidal depression or Viibryd’s nausea that gives Felbatol (felbamate) some serious competition.
    • For Brintellix it looks like indigestion worse than Abilify that can become full-on peptic ulcers.
  • Few dosage options.

Interesting Stuff your Doctor Probably didn’t Tell You about Brintellix

It’s safe for professional guinea pigs to drive after taking 10 mg of Brintellix. Even after taking it for a couple of days in a row.

This is the first time I’ve seen a driving test in a PI sheet. They actually tested the “operation of heavy machinery” scenario. Hats off to Takeda & Lundbeck for some of the most thorough testing done on a med I’ve ever seen.

Best Known for

I don’t know about anyone else, but to me it seems like the drug more incompetent doctors will misprescribe this side of Oxycontin.

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« Brintellix’s Side Effects, Warnings, etc. | Brintellix’s Pharmacology »

Last modified on Wed, 04 May, 2016 at 16:42:05 by JerodPoorePage Author Date created Thursday, 02 October 2014 at 15:17:50
“Brintellix (vortioxetine): Pros and Cons” by Jerod Poore is copyright © 2014 Jerod Poore Published online 2014/10/02

Brintellix, and all other drug names on this page and used throughout the site, are the trademarks of someone else. Brintellix’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

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