|US brand name: Abilify|
|Generic name: aripiprazole|
Abilify’s Pros and Cons
- As it sort of acts as a Parkinson’s/RLS med, so you’re somewhat less likely to get a couple of the more annoying AP side effects - most movement disorders and those involving prolactin.
- The anticholinergic side effects are also less likely than other APs.
- The long half-lives of of Abilify and its active metabolite mean you don’t have to worry about a dosing schedule, and you can even take a tablet every other day.
- Since it kind of acts like a Parkinson’s/RLS med, you can get the oddball side effects of a Parkinson’s/RLS med, like pathological gambling.
- That also means you can’t take another dopamine agonist to deal with AP-induced movement disorders. So if you do get EPS and want to keep taking Abilify, you’ll need to take a potent anticholinergic like Cogentin, and probably wind up getting anticholinergic side effects after all.
- Abilify’s long-ass half-lives mean if you two don’t get along you can be stuck with the side effects for at least one, and possibly two weeks after you stop taking it.
Interesting Stuff your Doctor Probably didn’t Tell You about Abilify
Abilify is the first third-generation antipsychotic (TGA) to hit the US market. TGAs are defined as being partial agonists at dopamine D2 receptors, and that’s what makes them act sort of like Parkinson’s/RLS meds. So, unlike Zyprexa, Abilify doesn’t just mask movement disorders by being a potent anticholinergic, it tries to prevent them from happening in the first place.
Best Known for
The Hiccups of Death. AKA the Abilify Burp.