Brand & Generic Names; Drug Classes
|US brand name: Remeron|
|Generic name: mirtazapine|
|Primary drug class: Antidepressants|
|Additional drug class(es): Tetracyclic Antidepressant Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)|
Approved & Off-Label Uses (Indications)
Remeron’s US FDA Approved Treatment(s)
Major depressive disorder
Uses Approved Overseas but not in the US
Off-Label Uses of Remeron
- Sleep Disorders
- Bipolar Depression
- And all sorts of things that keep you from sleeping well, like
- Chronic Fatigue
- Irritable Bowel Syndrome
- To treat some very specific auditory hallucinations
When & If Remeron Will Work
Remeron’s Usual Onset of Action (when it starts working)
- For depression: one to two weeks.
- For sleep: usually the night you take your first dose, the second night at the latest. If Remeron doesn’t make you tired at 15mg a night, don’t bother.
Likelihood of Working
Taking and Discontinuing
How to Take RemeronFor adults with MDD ,
The initial dosage is 15 mg once a night .If no improvement is felt within two weeks, that may be increased to 30mg. If you’re still not feeling better a month after that, you can go up to 45mg and officially that’s it, although there are reports of some psychiatrists experimenting with doses up to 90mg. There are no other published dosage options for Remeron at this time, it’s just weird that way. 15, 30 or 45mg. Some of the more enlightened doctors are starting their patients at 7.5mg and titrating them in 7.5mg increments, and I’m all for that method. If I were you, and I got along with meds that messed with my serotonin, I’d insist on that. 7.5mg to start, up to 15mg after a week or two if no improvement, then 22.5mg after a month and so forth up to 45mg. I think the 90mg craziness is in response to Remeron poop-out, which is just exposing people to side effects for no good reason.
How to Stop Taking Remeron (discontinuation / withdrawal)
Your doctor should be recommending that you reduce your dosage by 7.5 - 15mg a day every week if you need to stop taking it, if not more slowly than that. Based on the 20–40 hour half-life.