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Two of the most important things to know when deciding on which med is the best for a particular condition2: how likely is it to work and how long will it take.

The odds of a med working for a particular condition and how long it generally takes to work should be fairly easy to nail down, and not need to be summed up by the Internet shorthand YMMV (Your Mileage May Vary). Aside from it being hard enough to get an accurate diagnosis when brain cooties are involved, why is it so difficult to figure out if Invega is right for you and how long it will take for you to know that?

  • Because no one is quite sure exactly what causes various conditions.
  • Which is further complicated when everything is a spectrum disorder (e.g. bipolar 1, bipolar 2, all the others planned for DSM-V).
  • And they’re never really sure about how Invega works in the first place.
  • Plus, if you have more than one condition for which you’re taking one or more medications to treat, things get really complicated.
  • None of which is helped by studies that produce contradictory results, if they aren’t questionable in the first place.3

See our page on the tests researchers use to measure the efficacy of medications, including during clinical trials to get FDA approval.

1.  How Long Until Invega (paliperidone) Starts Working1

Like all antipsychotics you’ll feel something the next day. By the time you reach a steady state, usually in 4 to 5 days, you’ll pretty much know if Invega is going to do anything for you. Various studies and trials have shown positive results in 2 to 7 days, with 2 to 4 days being typical.

2.  Likelihood Invega (paliperidone) Will Work for its Approved Conditions

  • As the only drug with FDA approval to treat schizoaffective disorder - other than Clozaril’s approval to treat recurrent suicidal behavior - it doesn’t have a lot of competition.
  • According to Stahl, between five and 15% of people who take Risperdal or Invega respond well enough to hold down real jobs and live independently.

3.  Likelihood Invega (paliperidone) Will Work for Off-Label Applications

4.  How Invega (paliperidone) Compares with Other Meds for its Approved Treatments

It’s just a case report, but Risperdal gave this lady hepatitis and it went away after they switched her to Invega.

5.  How Invega (paliperidone) Compares with Other Drugs for Off-Label Treatments

‹ Expanded How to Take and Discontinue | Invega Index | Expanded Pharmacokinetics & Noted Drug-Drug Interactions ›
Crazy Meds Comprehensive Invega pages

Bibliography

1 In fancy doctorspeak: Time-to-response, or response time, or response begins at, or something with "response" in it. "Onset" refers to when the symptoms of a condition first appeared (presented). The only time you'd use "onset" with a drug is when side effects are involved.

2 Assuming you were correctly diagnosed in the first place.

3 Keep in mind that according to one study, most drug studies will skew in favor of the med made by the company that sponsored the study.* That's one of my favorite "no shit Sherlock" studies, although it did help in getting conflicts of interest showing up on papers.
Two additional papers along similar lines are Why Current Publication Practices May Distort Science** and Why Most Published Research Findings Are False***. So in addition to the books we use as source material, this is why we also factor a lot of anecdotal evidence (personal experience, experiences of people we know, case reports, what people have sent us in e-mail, and what is posted all over the Internet) into our conclusions regarding the likelihood of meds working, the prevalence of various side effects, etc.
While the drug companies are getting a lot more transparent and publishing more data in the PI sheets regarding the results of the clinical trials, they still don't publish how many times a drug failed a clinical trial.****


Date created 10 Jun 2011 - 17:09 Page Creator: girrl88 Last edited by:

Invega’s Expanded Efficacy and Comparisons with Other Meds is copyright 2011 girrl88

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*While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

‘Everything is true, nothing is permitted.’ - Jerod Poore


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