Highlighting uses, dosage, how to take and discontinue

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Asendin’s Side Effects, Warnings, etc. >>

Brand & Generic Names; Drug Classes

US brand name: Asendin
Generic name: amoxapine

Drug Class(es)

Primary drug class: Antidepressants
Additional drug class(es): Antipsychotics, Tricyclic & Tetracyclic Antidepressants

Approved & Off-Label Uses (Indications)

Asendin’s US FDA Approved Treatment(s)

Neurotic or reactive depressive disorders

Uses Approved Overseas but not in the US

Endogenous and psychotic depressions

Off-Label Uses of Asendin

Schizophrenia (One of numerous studies on this use)



When & If Asendin Will Work

Asendin’s Usual Onset of Action (when it starts working)

One to two weeks. Tetracyclics are fast. You’ll feel something within a couple of days.

Likelihood of Working

Taking and Discontinuing

How to Take Asendin

The initial dose is 50mg two to three times daily. After two to three weeks that may be increased to 100mg two to three times daily. Presuming this stuff works, the maintenance dose of 200–300mg may then be taken all at once at bedtime, but anything above 300mg a day needs to be split into two, or even three doses a day.

Inpatients may receive up to 600mg a day.

Given the incidence of AP-related side effects, you and your doctor should seriously discuss any increase above 200mg a day. You’d probably know by then if it’s going to be doing something positive for you.

How to Stop Taking Asendin (discontinuation / withdrawal)

Tri/tetracyclics don’t have much of a discontinuation syndrome. Depending on why you need to stop taking it, reducing your dosage by 50–100mg a day each week should be relatively painless.

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Last modified on Fri, 08 May, 2015 at 14:41:44 by JerodPoorePage Author Date created Monday, 28 January 2013 at 15:05:38
“Asendin (amoxapine): Uses and Using” by Jerod Poore is copyright © 2013 Jerod Poore Published online 2013/01/28

Asendin, and all other drug names on this page and used throughout the site, are the trademarks of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



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