Highlighting uses, dosage, how to take and discontinue

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Abilify’s Side Effects, Warnings, etc. >>

Brand & Generic Names; Drug Classes

US brand name: Abilify
Generic name: aripiprazole

Drug Class(es)

Primary drug class: Antipsychotics
Additional drug class(es): MoodStabilizers, Antidepressants

Approved & Off-Label Uses (Indications)

Abilify’s US FDA Approved Treatment(s)

Schizophrenia in adults & adolescents ; Bipolar in adults & children over 10 ; as an add-on to antidepressants for depression in adults ; Irritability associated with Autistic Spectrum Disorder (ASD) in pediatric patients ; and Psychomotor agitation associated with Schizophrenia or Bipolar Mania

Uses Approved Overseas but not in the US

Off-Label Uses of Abilify

Schizoaffective disorder , bipolar depression , monotherapy for depression-spectrum disorder , delusional disorders without psychoses , OCD , Parkinson’s .



When & If Abilify Will Work

Abilify’s Usual Onset of Action (when it starts working)

Faster than Seroquel, but slower than most other AAPs. I.e. 3–7 days, with 3 days more likely (but not always) when adding Abilify to an AD (or anything else) and 7 days more likely when using Abilify by itself.

Likelihood of Working

Given its activating nature, Abilify is probably more likely to work as an add-on to treat depression or bipolar disorder depression than as monotherapy for bipolar disorder.

I don’t yet have enough data for schizophrenia. This article shows 5mg a day takes 3-5 weeks to start working, and only enough better than placebo to get approved by the FDA. And that’s Seroquel territory of taking forever.

Taking and Discontinuing

How to Take Abilify

Manufacturers’ Recommendations

As with many APs, Otsuka & BMS recommend you just start at the target dosage. That’s 10 to 15 mg once daily for adults with Schizophrenia , 15 mg once daily for adults with Bipolar Disorder as monotherapy, and 10–15mg a day for bipolar when taken with Depakote or lithium. The maximum dosage is 30mg a day, and you should wait at least two weeks before increasing the dosage.

The only application where you start at a low dosage a move up is when you add it to an antidepressant (AD) for depression. That’s when they recommend you start at 2–5mg a day, work up to 5–10mg a day, and the maximum dosage is 15mg a day, and you should wait at least a week before increasing the dosage.

Crazymeds’ Suggestions

Our suggestion to discuss with your doctor: if you’re not crazy enough to be hospitalized, follow the instructions for using Abilify with an antidepressant, even if you’re taking it by itself (or with another drug) for bipolar disorder or schizophrenia.

How to Stop Taking Abilify (discontinuation / withdrawal)

With its long-ass half-lives, Abilify is a lot easier to discontinue than most meds, and severe rebound symptoms are less likely as well. Reduce your dosage by 5mg a day every 5–7 days. Every 3 days if you really need to withdraw faster than that.

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Last modified on Mon, 11 May, 2015 at 19:17:33 by JerodPoorePage Author Date created Tuesday, 29 November 2011 at 11:57:45
“Abilify (aripiprazole): Uses and Using” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/11/29

Abilify, and all other drug names on this page and used throughout the site, are the trademarks of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



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