Highlighting uses, dosage, how to take and discontinue


Latuda’s Side Effects, Warnings, etc. >>

Brand & Generic Names; Drug Classes

US brand name: Latuda
Generic name: lurasidone

Drug Class(es)

Primary drug class: Antipsychotics
Additional drug class(es): Second Generation Antipsychotic / Atypical Antipsychotic (SGA / AAP), MoodStabilizers, Antidepressants

Approved & Off-Label Uses (Indications)

Latuda’s US FDA Approved Treatment(s)

  • Schizophrenia
  • Bipolar Depression (officially: Depressive episodes associated with Bipolar I Disorder)

Uses Approved Overseas but not in the US

So far only Latuda’s approval in Canada is the same as that in the US.

  • In Australia, Britain, the EU, and Switzerland Latuda is approved only to treat schizophrenia, but not bipolar.
  • In Japan Latuda is approved to treat bipolar depression, and is still undergoing trials for schizophrenia. It’s also pending approval as maintenance therapy for bipolar 1.
    • Not yet approved for schizophrenia in Japan is even more hilarious than not being approved at all in Ireland, as lurasidone was developed by Dainippon Sumitomo Pharma in freaking Osaka!
    • And is manufactured in Ireland for distribution in Britain and the rest of the EU.
  • Pending approval to treat schizophrenia in China and Taiwan.1, 2

Off-Label Uses of Latuda

When & If Latuda Will Work

Latuda’s Usual Onset of Action (when it starts working)

Like most antipsychotics you should feel Latuda doing something positive within one or two days.

Likelihood of Working

Although the sample sizes from the field (i.e. what I can find on teh interwebs) are a lot smaller, Latuda seems to be more effective for schizophrenia than bipolar disorder. But I get the impression that people with schizophrenia are just more willing to put up with side effects than the bipolar. I know from 14 years of reading support groups and related sites that the bipolar are often usually whiny babies when it comes to side effects, so I’m pretty sure it’s not a question of efficacy but who is willing to put up with what for how long.

Bipolar Disorder


Taking and Discontinuing

How to Take Latuda

Manufacturer’s Recommendations

Sunovion recommends:

The recommended starting dose of LATUDA is 40 mg once daily. Initial dose titration is not required. LATUDA has been shown to be effective in a dose range of 40 mg/day to 160 mg/day. The maximum recommended dose is 160 mg/day.

 Latuda PI sheet

Crazymeds’ Suggestions

Given how freaking potent Latuda is, and that they make a 20mg tablet, starting with 20mg is something worth discussing with your doctor. It all depends on how crazy you are at the moment, or if you’re currently taking an antipsychotic and the plan is to switch you to Latuda.

You must take Latuda with food, at least 350 calories. Sunovion has now spelled out this requirement as clearly as Pfizer has with Geodon. If you don’t take your Latuda with food it’s the same as if you’re taking a little less than half of your dosage.

While it’s usually a toss-up as to if you should take some in the morning or at night, based on what little I’ve found out, start by taking it in the morning. Latuda might still put you to sleep, but the odds are in favor of it waking you up more than knocking you out.

How to Stop Taking Latuda (discontinuation / withdrawal)

Reduce your dosage by 20 to 40mg a day every five days to a week.

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1 我的反复道歉。

2 自由台湾万岁!

Last modified on Fri, 08 May, 2015 at 15:11:53 by JerodPoorePage Author Date created Tuesday, 14 May 2013 at 09:18:44
“Latuda (lurasidone): Uses and Using” by Jerod Poore is copyright © 2013 Jerod Poore Published online 2013/05/14

Latuda, and all other drug names on this page and used throughout the site, are the trademarks of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.

Page design and explanatory material by Jerod Poore, copyright © 2003 - 2015. All rights reserved. See the full copyright notice for full copyright details.
Don’t automatically believe everything you read on teh Intergoogles. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. For more details see the Crazymeds big-ass disclaimer.

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