side effects, dosage, reviews, how to take & discontinue, uses, pros & cons, and more

> Zoloft (sertraline) Overview


Zoloft Article Index | Brand and Generic Availability

Brand & Generic Names; Drug Class

US brand name: Zoloft
Generic name: sertraline
Drug Class: Antidepressants
Learn More about Zoloft’s Generic & Worldwide Availability

Zoloft’s Approved & Off-Label Uses (Indications)

US FDA Approved Treatment(s)

Major depressive disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Posttraumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAnD)

Popular Off-Label Uses

Generalized Anxiety Disorder (GAD), Eating Disorders, Depression in people with a variety of coronary problems, Menopause symptoms

Learn More about Zoloft’s Approved & Off-label Uses

How Long Until Zoloft Starts Working (Onset of Action)

Like all SSRIs anywhere from a couple days to over a month, although you should more awake and energetic in two to four days. If you don’t feel any positive benefit after four-six weeks, then you should talk to your doctor about either another SSRI or trying a med that hits another neurotransmitter.

Likelihood of Working

Zoloft is better for conditions in the anxiety spectrum than those in the depression spectrum. Which is funny given how agitated and nervous it makes a lot of people feel. Zoloft does work well for depression defined by sleeping too much, eating too much, and withdrawing from the world. Learn how Zoloft Compares with Other Drugs

How to Take Zoloft

In the PI sheet Pfizer recommends:

  • 50mg a day for MDD and OCD. That’s where you start, that’s where you stay.
  • For PTSD, panic & social anxiety disorders - start at 25mg a day and after a week increase it to 50mg a day.

We suggest:

  • Everybody starts at 12.5–25mg and waits at least two weeks, if you can, before increasing by 12.5–25mg a day.
  • And increase the dosage only if you need to.

Get mugged at Straitjacket T-shirts for mugs to wash down your antidepressants. 11oz $13 & 15oz $14
Depression Sucks! mugs at Straitjacket T-shirts
Depression Sucks!
Fuck Anxiety mugs at Straitjacket T-shirts
Fuck Anxiety
Mentally Interesting mugs at Straitjacket T-shirts
Mentally Interesting
Fuck OCD mugs at Straitjacket T-shirts
Fuck OCD

How to Stop Taking Zoloft (Discontinue, Withdrawal)

The usual way with SSRIs. Reduce your dosage by 12.5–25mg each week. If the discontinuation syndrome is too harsh you have two options, getting a prescription for the oral solution and reducing your dosage by whatever you can tolerate, or getting a prescription for 10mg fluoxetine capsules and take 20mg a day (if you’re at 25mg of Zoloft) for two weeks and 10mg a day for another two weeks. Learn More about Taking and Discontinuing Zoloft



Zoloft’s Pros and Cons

Pros

The slight, but noticeable, dopamine action Zoloft has is often enough to get you out of bed and back to work within a couple of days. You might still be depressed for another two-four weeks, but at least you don’t have to lie in bed staring at the ceiling and ruminating on how much your life sucks. It also makes weight gain less likely.

Cons

The slight dopamine action Zoloft has makes it the worst Serotonin-[sorta-]Selective Reuptake Inhibitor to take if bipolar is known or suspected. Definitely the worst to have taken if bipolar was a surprise. While the dopamine action is in the right place to make you sweaty and nervous (like Wellbutrin) it’s nowhere near the right place to prevent sexual side effects.

Interesting Stuff your Doctor Probably didn’t Tell You about Zoloft

If you take the tablets with food you’ll get a 25% increase in Zoloft’s peak plasma - the most you’d have in your blood - and it will happen faster, dropping from 8 hours to 5.5.
If you take the oral concentrate with food you won’t get any more out of it, but it will take longer to reach that peak amount, from 5.9 to 7 hours.
Increased and/or delayed peak plasma when taking meds with food happens all the time. But these numbers only make sense if the volunteers were professional lab rats.

Best Known for

The ad campaign featuring rolling blobs. Letting people know they’re bipolar with a big, fat, dysphoric mania.
In-Depth Pros & Cons

Shirts to swipe from
Crazymeds’ Clothes Line.
See more ways to let my
ADs express your feelings
at Straitjacket T-shirts.Shirts, hoodies & more.
$14-$51
FuckDepression shirts at Straitjacket T-shirts
Fuck Depression
Medicated for Your Protection shirts at Straitjacket T-shirts
Medicated for Your Protection
Anxiety Sucks! shirts at Straitjacket T-shirts
Anxiety Sucks!
Team Bipolar shirts at Straitjacket T-shirts
Team Bipolar

Don’t worry about buying one. Windows shop and share the designs you’d like to buy. Do you have anything better to do right now?


Zoloft’s Side Effects (Adverse Reactions)

Typical Side Effects

The usual for SSRIs - headache, nausea, dry mouth, sweating (more than most SSRIs) , insomnia, constipation or diarrhea, and loss of libido.

Uncommon Side Effects

Sweatiness, like headachegetting really sweaty all the time. Although not uncommon for SSRIs, Zoloft is a very “nervous” drug, as it can sometimes make you sweaty, shaky and generally uncomfortable in your own skin, more so than the others in this class. Which I find hilariously ironic, as it’s approved and fairly effective for panic disorder and social anxiety disorder, and used off-label for generalized anxiety disorder.

Freaky Rare Side Effects

Melanin pigmentation disturbance, echolalia, priapism, and persistent genital anesthesia. Hmmm, I wonder if Michael Jackson used to take Zoloft…

Learn More about Zoloft’s Side Effects.
TMI at times


Stick to your AD-based treatment plan with buttons and magnets. 2.25″ $4 & 3.5″ $4.50
Medicine Is The Best Medicine buttons at Straitjacket T-shirts
Medicine Is The Best Medicine
Fuck Depression buttons at Straitjacket T-shirts
Fuck Depression
Team OCD buttons at Straitjacket T-shirts
Team OCD
I <3 Wellbutrin buttons at Straitjacket T-shirts
I <3 Wellbutrin


What You Really Need to be Careful About

While every antidepressant was slapped with a warning about suicidal thoughts and behavior during the height of anti-psychiatry hysteria, Zoloft is actually one you need to be especially careful with. Like a large number of the instances when that sort of thing happened, it was due to the person being bipolar. It doesn’t help that Zoloft is the only SSRI where you can actually kill yourself with a month’s supply of pills (assuming an especially high dosage of 150–200mg a day, which some people actually take).

Zoloft’s Black Box and Other Warnings, Pregnancy Category, etc.

Pharmacology

sertraline’s Half-Life & How Long Until It Clears Your System

Plasma half-life: Half-life: 26 hours, clearance: five to six days.

sertraline’s Pharmacokinetics Information Overload

Half-life is the average time it takes for you to process half of the drug’s active ingredient. If a drug has a half-life of around 24 hours and you take a dose of 100mg, you’ll have roughly the equivalent a 50mg dose after one day, a 25mg dose after two days, and so on. The rule of thumb is: multiply the half-life by five and you get how long it is for the dose you took to be cleared from your bloodstream, so there’s nothing swimming around to attach itself to your brain and start doing stuff1. That’s called “plasma clearance.” Complete clearance is a complex equation based on a lot of factors which may or may not: be published in the PI sheet, include personal data like your weight, or even completely figured out by corporate and independent researchers. It usually winds up being 2–5 days after plasma clearance no matter what2, but can take weeks. Sometimes a drug will clear from your brain and other organs before it clears from your blood. If we’ve found the complete clearance, or how to calculate it if it requires things like your weight and what your piss looks like, you’ll find that on sertraline’s pharmacokinetics page.

How sertraline Works

the current best guess at any rate
Sertraline is the second-most potent SSRI on the US market (Paxil is the most potent)3. With its action as a dopamine reuptake inhibitor and its effect on the 5HT1A receptors, Zoloft probably affects dopamine enough, directly and indirectly, to have a meaningful impact, both good and bad, on side effects. Zoloft may also work on the sigma 1 receptors, and that would explain why it’s so effective for anxiety disorders.

Learn More than You Probably Ever Wanted to Know about How sertraline Works
AKA mechanism/method of action, pharmacodynamics


These will stick around longer than AD side effects. More ways to be stuck-up at Straitjacket T-shirts. Individual stickers only $5. Packs of 10 and 50 available.
Medicine Is The Best Medicine stickers at Straitjacket T-shirts
Medicine Is The Best Medicine stickers
Fuck Depression stickers at Straitjacket T-shirts
Fuck Depression stickers
PTSD Sucks! stickers at Straitjacket T-shirts
PTSD Sucks! stickers
Fuck Bipolar bumper stickers at Straitjacket T-shirts
Fuck Bipolar bumper stickers

You don’t have to buy anything. Look around the store. Tweet what you like to your Pinbook Circle. Do you have anything better to do right now?


Ratings, Reviews, Comments, PI Sheet, and More

Zoloft Comments

While Zoloft is no more likely to trigger mania than any other SSRI, due to that dopaminergic kick the symptoms it triggers are a lot worse. Zoloft just gets you way more agitated and sets of these nasty dysphoric manias in the bipolar, which can be a very harsh way to discover that one is bipolar. With the other SSRIs and SNRIs it’s a coin toss as to whether they’ll trigger euphoric manias that will send you on spending sprees or marrying people you just meet, or trigger dysphoric manias that make you destroy all the furniture in a room. But with Zoloft the odds are heavily in favor of the dysphoric mania. That may be why the poor little Zoloft lozenge quit shilling Zoloft so heavily for depression, and now primarily touts its efficacy for social anxiety, panic disorder, PTSD, and PMDD. Then again it could be that Zoloft is just testing better in studies for its other approved uses. In any event, that’s you need to be extra careful with Zoloft, more than most others antidepressants, when it comes to watching out for suicidal thoughts and behavior.
Extended Comments
As if I didn’t go on long enough already.

Zoloft Ratings & Reviews, and Consumer Comments & Experiences

Rate Zoloft

Give your overall impression of Zoloft on a scale of 0 to 5. Detailed ratings and reviews are available on the Zoloft Ratings & Reviews Page.

Get all critical about Zoloft

3.5 stars Rating 3.3 out of 5 from 347 criticisms.
Vote Distribution: 40 – 20 – 34 – 42 – 118 – 93


Rate this article

If you’re still feeling judgmental as well as just mental4, please boost or destroy my self-confidence by honestly (and anonymously) rating this article on a scale of 0 to 5. The more value-judgments the better, even if you can criticize my work only once.

Get all judgmental about the Zoloft (sertraline) Overview

4 stars Rates 3.8 out of 5 from 149 value judgments.
Vote Distribution: 13 – 2 – 3 – 15 – 60 – 56


Discussion board

Consumer experiences with and questions about Zoloft on Crazymeds Zoloft discussion board. Sign up for a free account to post your own.

More Allegedly Useful Links. Mostly official sites, PI sheet-equivalents5 from countries other than the US, and reviews from other consumer review sites.


Enable CafePress’ delusions they’re actual competition to Amazon. Assorted useless crap $5 - $85
Medication Time clock
Medication Time clock
Pile of Pills pillbox
Postmodern Pillbox
Meds Help framed tile
Psychological Hang-Ups
Batshit Crazy field bag
Emotional Baggage
Merry RxMas - The Last Tree on the Lot Card
Merry RxMas Cards

You don’t need to buy anything. Browse and share if you have nothing better to do.


It’s always a good idea to check for drug-drug interactions yourself. Just because most people in the crazy meds business know about really important interactions (e.g. MAOIs and a lot of stuff, warfarin and everything on the planet) doesn’t mean the person who prescribed your meds told you about them, or the pharmacist has all the meds you take at their fingertips like they’re supposed to. Or they have the time to do their jobs properly when not dealing with complete idiots or playing Angry Farmers on the Faecesbooks.



Keep Crazymeds on the air.
Donate some spare electronic currency
you have floating around The Cloud
Display your mad pride.    
Tell your imaginary friends about Crazymeds.

References

  1. Zoloft’s Full US Prescribing Information
  2. Faught, Edward. “Topiramate in the treatment of partial and generalized epilepsy.” Neuropsychiatric disease and treatment 3.6 (2007): 811-821.

Obach, R. Scott, Loretta M. Cox, and Larry M. Tremaine. “Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study.” Drug metabolism and disposition 33.2 (2005): 262-270.

Kobayashi, Kaoru, Tomoko Ishizuka, Noriaki Shimada, Yoshitaka Yoshimura, Kunitoshi Kamijima, and Kan Chiba. “Sertraline N-demethylation is catalyzed by multiple isoforms of human cytochrome P-450 in vitro.” Drug metabolism and disposition 27, no. 7 (1999): 763-766.

Stahl, Stephen M. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Third edition Cambridge University Press 2008. ISBN:978–0521673761

Julien, Robert M. Ph.D, Claire D. Advokat, and Joseph Comaty Primer of Drug Action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs 12th edition Worth Publishers 2011. ISBN:978–1429233439

Stahl, Stephen M. The Prescriber’s Guide (Essential Psychopharmacology Series) Third edition Cambridge University Press 2009. ISBN:978–0521743990

Virani, Adil S., K. Bezchlibnyk-Butler, and J. Jeffries Clinical Handbook of Psychotropic Drugs 18th edition Hogrefe & Huber Publishers 2009. ISBN:978–0889373693

Mosby’s Drug Consult 2007 (Generic Prescription Physician’s Reference Book Series) © 2007 ISBN:978-0323040587 An imprint of Elsevier

Instant Psychopharmacology 2nd Edition Ronald J. Diamond MD © 2002. ISBN:978-0393703917 Published by W.W. Norton.

The Complete Guide to Psychiatric Drugs Edward Drummond, MD © 2000. ISBN:0471353701 Published by John Wiley & Sons, Inc.

PDR: Physicians’ Desk Reference 2010 64th edition

Healing Anxiety & Depression Daniel G. Amen, M.D., and Lisa C. Routh, M.D. © 2003. Published by G.P. Putnam’s Sons.

Sheldon Preskorn’s Applied Clinical Psychopharmacology www.preskorn.com Sheldon Preskorn, M.D. Chief Executive Officer of the Clincal Research Institute and a Professor in the Department of Psychiatry and Behavioral Sciences at the University of Kansas School of Medicine - Wichita Last Accessed 08 July 2014

Zoloft Article Index | Brand and Generic Availability

1 Based on Julien's calculations from A Primer of Drug Action, the half-life multiplied by five is the generally accepted estimate of how long it takes a single dose of any given drug to be eliminated from the blood stream/plasma of someone with a normal metabolism. That's also the rough estimate for steady stage if they can't get, or won't provide a number for that.

2 For crazy meds. I have no idea what the average complete clearance is for other types of medications. For all I know there are drugs that utterly vanish from your system in under five passes, and others that won't let go of your squishy bits for years after you stop taking them.

3 In terms of sheer raw power of pure sertraline at serotonin transporter binding sites. All sorts of other factors are involved in determining a drug's potency. As I write all over the place "potency" and "efficacy" are two completely different things. See the pages on SSRI & SNRI Dosage Equivalents and Pharmacokinetics for more information.

4 Thank you! I'll be here all weak. Be sure to tip your content provider. And don't try the veal, it's cruelicious!

5 These include: Canada's Product Monographs (PM), New Zealand's Medicine Data Sheets (MDS), the EU's European Public Assessment Reports (EPAR), and the Summary of Product Characteristics (SPC) used in Britain, Ireland, and many other places.


If you have any questions not answered here, please see the Crazymeds Zoloft discussion board. We welcome criticisms of the articles, notifications of bad links, site problems, consumer experiences with medications, etc. I’m not always able to write back. Hence I never answer questions about meds via e-mail that are answered by this or other articles. Especially if they have been repeatedly asked on the forum. That’s why we write these damn things. Questions about which meds are best for your condition should also be asked on the forum; because this is a free site, so the price of admission is making things easier for somebody else searching for the same answer. We don’t deal with children on the forum or in private because after doing this for ten years I don’t have the emotional stamina to deal with kids who have brain cooties. How to contact Crazymeds. — Jerod Poore, CME, Publisher Crazymeds (crazymeds.us)


Last modified on Monday, 14 July, 2014 at 12:14:27 by JerodPoorePage Author Date created Wednesday, 06 April 2011, at 14:28:00
“Zoloft (sertraline): a Synopsis for the Educated Consumer.” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/04/06
Citation options to copy & paste into your article:
Plain text:Poore, Jerod. “Zoloft (sertraline): a Synopsis for the Educated Consumer.” Crazymeds (crazymeds.us). (2011 ).
with Microdata: <span itemprop='citation'>Poore, Jerod. "Zoloft (sertraline)." <em>Crazymeds (crazymeds.us)</em>.(2011 ).</span>
Linked:<a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='http://www.crazymeds.us/pmwiki/pmwiki.php/Meds/Zoloft'>"Zoloft (sertraline): a Synopsis for the Educated Consumer."</a>. <a href="http://www.crazymeds.us/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.us)</em></a>. (2011 ).
with Microdata:<span itemprop='citation'> <a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='http://www.crazymeds.us/pmwiki/pmwiki.php/Meds/Zoloft'>"Zoloft (sertraline): a Synopsis for the Educated Consumer."</a>. <a href="http://www.crazymeds.us/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.us)</em></a>. (2011 ).</span>

Zoloft, and all other drug names on this page and used throughout the site, are a trademark of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.




Page design and explanatory material by Jerod Poore, copyright © 2004 - 2014. All rights reserved.
Keep up with Crazymeds and and/or my slow descent into irreparable madness boring life. Pick your preferred social media target(s):

Almost all of the material on this site is by Jerod Poore and is copyright © 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, and 2014 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That’s usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that’s OK to just do. Go for it! Please. As long as you include this copyright notice and something along the lines of following disclaimer, I’m usually cool with it.



All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
Know your sources!
Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained through our personal experience and the experiences family, friends, what people have reported on various reputable sites all over teh intergoogles, the medications’ product information / summary of product characteristic (PI/SPC) sheets, and from sources that are referenced throughout the site. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Very little information about visitors to this site is collected or saved. From time to time I look at search terms used and which pages they bring up in an effort to make the information I present more relevant. And the country of origin, just because I’m geeky like that. That’s about it. Depending on how you feel about Schrodinger, our privacy policy should either assuage or exacerbate your paranoia.
Crazymeds is optimized for the browser you’re not using on the platform you wish you had. Between you and me, it all looks a lot cleaner using Safari or Chrome, although more than half of the visitors to this site use either Safari or Internet Explorer, so I’m doing my best to make things look nice for IE as well. I’m using Firefox and running Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. Use only as directed. Void where prohibited. Contains nuts. Certain restrictions may apply. All data are subject to availability. Not available on all mobile devices, in the 12 Galaxies Guiltied to a Zegnatronic Rocket Society, or in all dimensions of reality. Hail Xenu!

‘Everything is true, nothing is permitted.’ - Jerod Poore


1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.

3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas? I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion of anonymity. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.

Enable Crazymeds’ Financial Solvency!

Enable Crazymeds to keep spreading our knowledge. Donate some spare e-currency you have floating around The Cloud.

Improve Your Social Media Skills

Net.Presents

Follow our Highly Irregular Updates and Paranoid Rants Other News on All* Social Media

Crazymeds

Show us teh like™

Square this Circle


Sites That Probably Suck Less Than Crazymeds

Crazymeds Merchandise

You don’t have to buy anything.
Sharing what you’d like to buy
helps support this site.

Available at Straitjacket T-Shirts

Medicated for your Protection hoodie at Straitjacket T-Shirts

Clothes Hoist
T-Shirts, Hoodies & More $14-$55


Team Manic! mug at Straitjacket T-Shirts

Get Mugged
11oz $13 & 15oz $14


Merry RxMas Cards & Gifts at Straitjacket T-Shirts

Merry RxMas Cards & Gifts
3 Designs of cards, plus Merry ℞mas mugs and magnets.


Vaccines Cause Immunity bumpersticker at Straitjacket T-Shirts

Stuck Up
All stickers $5. Now Available in Packs of 10 & 50


Mentally Interesting button at Straitjacket T-Shirts

Button It!
2.25″ $4 & 3.5″ $4.50. Now Available in Packs of 10 & 100


Meds Help framed tile at Straitjacket T-Shirts

Psychological Hang-Ups
Posters, Prints & Framed Tiles $12 - $40


Mentally Interesting tote at Straitjacket T-Shirts

Emotional Baggage
Assorted Totes & Bags $18 - $35


Brain Cooties Aren't Contagious Magnet at Straitjacket T-Shirts

Magnetic Personality Disorders
2.25″ $4, Larger Sizes $4.50. Some Designs in Packs of 10 & 100


You don’t have to buy anything. Windows shop. Tweet what you like to your Pinbook circle. It might be less boring than whatever you’re doing now.

Burning Mind Books

Psychopharmacology tomes at Burning Mind Books

Books & Other Media for the Mentally Interesting

Replace my awful design choices with your own

Return to the Original Flavor

* Where I bother to get an account for the Crazymeds site.
I, on the other hand, am everywhere.
Just trying to make things easier for the sad, overweight, greasy sociopaths of the world.

dimension