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Click on these links to learn more about Keppra:

Basic Information About Keppra   Keppra's Side Effects  Keppra's Dosage, Discontinuation and Half-Life  Keppra's Effectiveness, Comparison with Other Meds and Ratings  How Keppra Works in Your Brain Page  Buying Keppra & Keppra PI Sheets  Special Effects & Issues with Keppra   Comments

 

Basic Information About Keppra (levetiracetam)

 

 

 

 

US Brand Name: Keppra
The link here will take you to the official website of the drug.

Generic Name: levetiracetam

Other Forms: Grape flavored suspension. (The one report we have is that the grape flavored suspension tastes like ass.)
Intravenous injection - but only as a temporary way to deal with those days when you can't swallow one of those big-ass pills.

What is Keppra: Keppra is an Anticonvulsant.  Also know as an anti-epileptic drug (AED) and mood stabilizer.
Read the section on this link for common effects and side effects for the entire class.

What are Keppra's FDA Approved Uses: Keppra is approved as adjunctive therapy (used with one or more other anticonvulsants) for partial onset epilepsy in adults and children over 4 years.  Approved November, 1999.  Partial seizures include:

  • Simple partial seizures - you're still awake (more or less), with symptoms such as one or two limbs spazzing out or wacky visual or other sensory distortions.  Think Alice in Wonderland, as Lewis Carroll must have had some serious temporal lobe issues.  The fist link will take you to a better explanation.  For a really detailed explanation of what a simple partial seizure is, click here.

  • Complex partial seziures - the people around you think you're just acting out to get attention.  In reality you have no control over what's happening.  Again, click there for the basics, click here for what neurologists think about this type of seizure.

Keppra is also approved to treat myoclonic seizures (E.g. an arm shoots out, your latté covers someone in line at the coffee shop, and you try to explain how it was an accident and how you'll cover the dry cleaning bill.) in adults and children.  This includes the wacky juvenile myoclonic epilepsy. Again officially it must be taken with one or more other anticonvulsants.

Keppra's Off-Label Uses:  Boy do we have off label uses!

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Keppra's pros and cons:

Pros: LOW side effect profile.  Much less chance of your flipping out on it when compared to other anticonvulsants (E.g. Keppra: 10% of epileptics with previous histories of psychiatric or serious epileptic flippage had issues.  Topamax:  24% of similar people had issues.Tends to make people smarter, not dumber like most anticonvulsants.  Even people starting with learning disabilities can get a bit of a boost. Also, unlike many anticonvulsants it's so easy on your liver you can take it after a freaking liver transplant! It starts working right away, and many people can start at or near the therapeutic dose if required-it was designed that way.  One researcher describes it as having, "close to ideal pharmacokinetic properties."

 

Cons: A lot of the side effects it DOES have are psychiatric. Reports from the field (a.k.a. anecdotal evidence) suggest the most common are the deep, sometimes suicidal depression. Another favorite is the Keppra rage, although this one seems to be overhyped.  Far less frequent, but still reported, are hallucinations - one woman I know with epilepsy had deep philosophical conversations with a ghost every night. And there's this case report of a kid getting a bit psychotic on Keppra.  Those kind of suck-especially when no one bothers to warn you that they might happen.

Check for Drug-Drug Interactions

Click on these links to learn more about Keppra:

Basic Information About Keppra   Keppra's Side Effects  Keppra's Dosage, Discontinuation and Half-Life  Keppra's Effectiveness, Comparison with Other Meds and Ratings  How Keppra Works in Your Brain Page  Buying Keppra & Keppra PI Sheets  Special Effects & Issues with Keppra   Comments

 

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Crazy Meds Home  Crazy Meds Talk   About Antidepressants   About SSRIs   About Anticonvulsants / Mood Stabilizers    About Atypical Antipsychotics   About Benzodiazepines   About Stimulants   Finding a Doctor    Sites with More Information     Support Group Sites    About Crazy Meds    Visit my autistic - bipolar - epileptic blog

 

Keppra in the News

Epilepsy in the News

Bipolar Disorder in the News

 

 

Dead tree references:

Physicians' Desk Reference Edition 59 Min Ko and Greg Tallis, Drug Information Specialists, et al. ©  2005. Published by Thomson PDR.

 

 

Neurology for Psychiatrists Gin S. Malhi, Manjit S. Matharu & Anthony S. Hale.  ©  2000. Published by Martin Dunitz

 

 

Mosby's 2004 Drug Guide David Nissen PharmD, Editor.© 2004.  An imprint of Elsevier.  The edition we're using isn't listed on Amazon.

 

 

End of books used for this article.

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Created Saturday, August 06, 2005

Last updated Friday, May 22, 2009

 

Content Copyright © 2005 Kassiane S.. Format Copyright 2005 Jerod Poore.  All rights reserved.

 

Almost all of the material on this site is copyright © 2002, 2003, 2004, 2005 and 2006 Jerod Poore. Except, of course, the PI sheets, those are the property of the drug companies who developed the drugs the sheets are about.  And any documents that are written by other people which may be posted to this site will remain the property of the original authors.  You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder.  That's usually me, so just ask first.  That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that's OK to just do.  Go for it!  Please.  As long as you include this copyright notice and the following disclaimer, I'm cool with it.

All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won't necessarily happen to you. Nobody on this site is a doctor, therapist, or a pharmacist. We don't portray them either here or on TV. Only doctors can diagnose and treat an illness. Some doctors tend to get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don't be a cyberchondriac, thinking you have every disease you see a website about, or that you'll get every side effect from every medication. Self-prescribing is just as dangerous.  All information on this site has been obtained through personal experience, the experiences of my friends, the experiences of people reported on online support groups, and from sources that are referenced throughout the site.  Know your sources!  As such the information presented here is not a substitute for real medical advice from your real doctor, just a compliment to it.  No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. All brand names of the drugs listed in this site are the trademarks of the companies listed after them in the pages about the drugs, even though those companies may or may not have been acquired by other companies who may or may not be listed in this site by the time you read this. Always read the PI sheet that comes with your medications and never ever throw them away.  If you didn't get a PI sheet, demand one.  Loudly.  Crazy Meds is not responsible for the content of sites we provide links to.  We like them, or they're paid advertisements, or they're something you should read to make an informed decision about a particular med.  Sometimes they're more than one of those things.  But what's on those sites is their business, not ours.  Very little information about visitors to this site is collected or saved. And from time to time I do look at search terms used to find it in an effort to make the information I present more relevant. Use only as directed. Void where prohibited.

 

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