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Strattera And Anger


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#1 In_Remission_ladywolf

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Posted 23 August 2007 - 05:47 PM

Ohmigod, I cannot believe that all of the archived posts from CrazyMeds Talk are gone! What a huge loss of valuable information and advice -- however, hats off to Jerod & Co. for finally getting a new Talk forum going again. It's been very hard not having it to reference. I, for example, have been on two meds that are new to me since CM Talk went down, and have had almost nowhere to turn for definitive, credible input from Those of Us Who Know. It's hard going crazy alone! (Well, luckily, I do have one similarly crazy friend whom I see almost every day, which helps us both enormously.)

Thank You, Jerod, for bringing this back!

Strattera. Yeah, I know, not officially an antidepressant -- on-label use is mainly for ADD and ADHD -- but being used more and more as an AD. I won't bore you with my history -- it's l-o-n-g, and probably a lot like your's. Have tried every AD known to man and womankind (and some compounded by Aliens, I am certain). Atypical antipsychotics, sleeping meds, tranqs...you name it, I've probably tried it.

And...drum roll...still crippled by depression and anxiety. My circumstances are quite dreadful right now, which isn't helping (never does)!

So...Strattera as My Drug of the Month. My second try with it, because the first two weeks I took it, I became even more anxious, horribly irritable, and downright suicidal. So I took a little sidetrack into Remeronland, but that was so freaky that it made Strattera look good by comparison...

So...I decided to try it again. (I have a mostly useless public health shrink whom I get to see by video once a month for 15 mins. if I'm lucky(?). What I DO have going for me is that I'm a psychotherapist myself, with twenty years in private practice, so I do know a lot about pharmacology, and mostly get to choose my own of the Month. Except Remeron -- that was his last diabolical offering!)

First week or two on 15 mg, and then 30 of Strattera, I did indeed feel more focussed, less upset by small things, better able to get the job done. But now, in about week three or four, anger is overtaking me, especially in the first few hours after I take my 30 mg. (I went up to 45 briefly, but cut back again when the irritability kicked in.) It's a hideous feeling -- this morning, I had the impulse to beat my wolfdog when she didn't come when I called her -- and I LIVE for my wolfdog Lady and her companion Poppers. I've never hurt an animal in my entire life and never will!

Road-rage, impatience, edginess -- all of the above and more. Terrible feelings.

So the question is: is this anger likely to go away, or worsen? Could it be dose-related, and might I actually have less of it if I do increase the dose to, say, 45 or 60, and try staying there for awhile? I know that Jerod recommends upping sodage (that was dosage!) by 15 mg. increments, which I've been doing.

I found a terrifying long thread in...let's see...wikipedia's talk forum, wikitalk, is it called?...about Straterra and rage, which scared the bejeesuz out of me. (It's called "Strattera and Mood Swings," I think.)

Please, others with Strattera experience, share with me and us. This stuff scares me, but then, they all do after 45 years of the Medication Crap-Shoot! And I am indeed feeling a bit better on it, apart from the anger.

BTW, only other psychomed I'm taking is a little Seroquel (25 mg.) just to put me to sleep.

Thanks, all!!

Ladywolf



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#2 Sasha

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Posted 23 August 2007 - 09:30 PM

First, I'm wondering if anyone's ever raised the possibility that you might fall somewhere on the bipolar spectrum, just because what you're describing with the Straterra sounds very like a dysphoric hypomania to me, and often people who've been diagnosed with unipolar depression, yet find minimal relief from treatment geared toward that diagnosis ultimately find themselves with a bipolar spectrum diagnosis, and respond to treatment aimed at that diagnosis much better and more quickly. Just an unasked for thought...

Second, I had a hideous time on Straterra, not so unlike what you're describing, I think. I was angry all the time, very reactive, doing a lot of crying, yelling, and breaking things. It only got worse as my dosage increased and as time went on. I felt much better, pretty quickly, once I stopped taking it. Your experience may be different, but for me, Straterra was truly awful.
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#3 StrungOutOnLife

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Posted 24 August 2007 - 05:36 AM

First, I'm wondering if anyone's ever raised the possibility that you might fall somewhere on the bipolar spectrum, just because what you're describing with the Straterra sounds very like a dysphoric hypomania to me, and often people who've been diagnosed with unipolar depression, yet find minimal relief from treatment geared toward that diagnosis ultimately find themselves with a bipolar spectrum diagnosis, and respond to treatment aimed at that diagnosis much better and more quickly. Just an unasked for thought...

Second, I had a hideous time on Straterra, not so unlike what you're describing, I think. I was angry all the time, very reactive, doing a lot of crying, yelling, and breaking things. It only got worse as my dosage increased and as time went on. I felt much better, pretty quickly, once I stopped taking it. Your experience may be different, but for me, Straterra was truly awful.

I did just that in a PM that I started typing last and only sent just now.
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#4 coverto

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Posted 24 August 2007 - 07:49 AM

I might tend to agree with the others.

Also, an observation that may or may not be useful. I discontinued Strattera, thinking I didn't need an AD anymore (I was wrong) and restarted. Having gone through titrating up twice now, I can make this observation - Strattera makes me feel really, really good, IMMEDIATELY, but only during the titration phase. Once I become stable on the dosage, the effects are more, though not wholly, transparent.

Your experience with Strattera sounds different from mine - I have recently felt a wee bit hypomanic (I am not diagnosed as BP) and felt a TAD more irritable and impatient with people, but nothing like what you describe.

I'll have to check out that mood swings discussion - my mood HAS been volatile lately, bouncing from focused hypomania to mild dysphoria - and both of those together - though I have been hyper-busy and under extreme stress by any objective measure. Hmmm...

Anyway, I'm starting to ramble now.. :mad:
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#5 In_Remission_annabrecker

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Posted 24 August 2007 - 10:08 AM

Strattera... oh for FUN. Lord. I had been taking it for 3 months and doing SO well on it... able to sit for the better part of a movie, standing still, even going fishing and being quiet. It was GREAT. A godsend.

Suddenly (and life circumstances definitely played a part in this) I went ballistic. I have never been so angry in my life. I also became extremely distrustful of everyone around me, and suspicious of my husband, my best friend and everyone else as well.

I ended up having suicidal ideations, even felt homicidal, and just went completely off the wall. Had my first psychotic break. Fun, fun.

The psych jerked me off it and I felt a little better, calmer, but still angry. That anger lasted for about 4 months after the fact, and was unbelievably painful to deal with.

That was my experience with Strattera, and I hope never ever to have to go through anything like that again. Being crazy is bad enough without help! lol
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#6 Jerod Poore

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Posted 24 August 2007 - 10:50 AM

ladywolf,


First, I'm wondering if anyone's ever raised the possibility that you might fall somewhere on the bipolar spectrum, just because what you're describing with the Straterra sounds very like a dysphoric hypomania to me, and often people who've been diagnosed with unipolar depression, yet find minimal relief from treatment geared toward that diagnosis ultimately find themselves with a bipolar spectrum diagnosis, and respond to treatment aimed at that diagnosis much better and more quickly.


I'm casting my vote on asking your doctor about a real evaluation for bipolar, and not one of those ten-question ones that come from the drug companies selling ever-so-profitable antipsychotics.

In any event, any antidepressant can cause symptoms as you describe, regardless of one's diagnosis. Tweaking norepinephrine just may not be the thing for you. Or, in the case of bipolar disorder, is not the thing for you without an anticonvulsant.
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#7 KG85

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Posted 24 August 2007 - 08:41 PM

Much like Sasha's reply I was extremely short tempered and irritable on strattera. I had the worst fight ive ever had in my life with my dad the second day I was on it and our fights were already *extremely* bad, but that one made the others seem tame.

Edited by Cyeic, 25 August 2007 - 07:21 AM.
Content - Full reason given via PM

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#8 In_Remission_weeaboo

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Posted 05 September 2007 - 12:51 PM

Reading this makes me glad I was on lamictal before starting the strattera. I was mostly zonked in the beginning, then I started noticing some concentration benefits. I've got too good coping skills to merit a proper ADD screening by the specialised pdocs who are the only ones allowed prescribe stimulants here. Socialised healthcare, though art a fickle mistress.

Anyways this has nothing to do with anger issues, sorry.

#9 Eeyore

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Posted 12 October 2007 - 11:44 AM

I just started Strattera today... I was actually really excited about it (FINALLY getting some help for ADD!) But these posts worried me. I am hoping not to get the angry mood swings. However, it seems like these effects are very similar to what people report on Wellbutrin, so I'm guessing it must be related to Norepinephrine somehow. My experience on Wellbutrin was overall good (though I ended up having a bad physical reaction, and can't take it). I did notice some of the short-temperedness, however, for me, the benefits far outweighed the drawbacks (wow, just like the book says! I'm really not lazy, stupid or crazy! Oh wait, I am crazy...). So I guess it really depends on what particular flavor of depression you have.
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#10 Sasha

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Posted 12 October 2007 - 01:19 PM

I just started Strattera today... I was actually really excited about it (FINALLY getting some help for ADD!) But these posts worried me. I am hoping not to get the angry mood swings. However, it seems like these effects are very similar to what people report on Wellbutrin, so I'm guessing it must be related to Norepinephrine somehow. My experience on Wellbutrin was overall good (though I ended up having a bad physical reaction, and can't take it). I did notice some of the short-temperedness, however, for me, the benefits far outweighed the drawbacks (wow, just like the book says! I'm really not lazy, stupid or crazy! Oh wait, I am crazy...). So I guess it really depends on what particular flavor of depression you have.


Keep in mind that the title of this thread attracted people who'd had trouble with Strattera, rather than those who'd had very successful experiences, and don't let it get you un-excited about a new med you haven't even been on for a full day yet.
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#11 Eeyore

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Posted 12 October 2007 - 05:09 PM

Keep in mind that the title of this thread attracted people who'd had trouble with Strattera, rather than those who'd had very successful experiences, and don't let it get you un-excited about a new med you haven't even been on for a full day yet.


Yeah, that sort of happens around here. I haven't found any other threads on strattera, was just curious what people thought about it. I read all about Jerod's experience on the main page which gave me some hope. I'm still excited about it (as exciting as starting a new med can me... not like, Daddy just bought me a pony excited). Just wondering if there was any weirdness I might want to be prepared for!

Edited by Eeyore, 12 October 2007 - 05:10 PM.

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#12 netsavy006

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Posted 02 December 2007 - 01:49 PM

I had an anger problem on Strattera and it never got better so I had to stop taking it after a week.
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#13 In_Remission_Desperately_seeking_sanity

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Posted 19 September 2011 - 05:44 PM

I am currently taking Strattera and have been for the last few months. I know what you mean about the anger. I have to say from my experience I am not sure its anger (in my case) but rather untreated anxiety. I suffer from ADHD, anxiety, depression, and OCD. While I do think strattera helps with my depression and ADHD, it does nothing for my anxiety levels or OCD. I have wanted to give up on it but have stuck through its ups and downs. I do take xanax for my anxiety but because it isn't time released it doesn't keep my anxiety and OCD at bay. I am currently looking for something to help better with my anxiety and OCD while still keeping the perks of Strattera.


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