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Trazodone Plus Benadryl -- Is It Ok?


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#1 In_Remission_pineapple

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Posted 15 July 2009 - 11:25 AM

Hey all,

So I take prozac 60 mg/day for ocd and it works well for me except it totally messes up the quality of my sleep so I take 50mg traz every night. The 50 mg traz works well for me, I feel much more rested in the morning. With my prozac/traz combo I do pretty well.

In fact I feel so good I decided to get pregnant.

Summer is here and I have really bad allergies. The worst allergies ever for me. I dunno if pregnancy makes it worse or something.
Let's put it this way -- I sneeze and cough so hard that it causes stress incontinence for me (I do think that is pregnancy-related), and the incontinence
got to be such a problem that I couldn't go out of my apartment and I also developed a painful diaper rash. I have more empathy for babies now.

But I can't take my old standby zyrtec 'cause I'm pregnant. The ob doc sez I can only take benadryl for allergies.

So I'm wondering if me and the fetus can take benadryl and traz at the same time or whether we'll end up loopy or I'll end up asleep at the wheel or something.
I DID ask my psychiatrist and well, he didn't know the answer. Guess he's never seen that combo before. Anyone try it? I do think benadryl is the same ingredient
that's also in Tylenol PM if that helps.

thanks
Pineapple



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#2 Nutter 6

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Posted 15 July 2009 - 12:18 PM

Hey all,

So I take prozac 60 mg/day for ocd and it works well for me except it totally messes up the quality of my sleep so I take 50mg traz every night. The 50 mg traz works well for me, I feel much more rested in the morning. With my prozac/traz combo I do pretty well.

In fact I feel so good I decided to get pregnant.

Summer is here and I have really bad allergies. The worst allergies ever for me. I dunno if pregnancy makes it worse or something.
Let's put it this way -- I sneeze and cough so hard that it causes stress incontinence for me (I do think that is pregnancy-related), and the incontinence
got to be such a problem that I couldn't go out of my apartment and I also developed a painful diaper rash. I have more empathy for babies now.

But I can't take my old standby zyrtec 'cause I'm pregnant. The ob doc sez I can only take benadryl for allergies.

So I'm wondering if me and the fetus can take benadryl and traz at the same time or whether we'll end up loopy or I'll end up asleep at the wheel or something.
I DID ask my psychiatrist and well, he didn't know the answer. Guess he's never seen that combo before. Anyone try it? I do think benadryl is the same ingredient
that's also in Tylenol PM if that helps.

thanks
Pineapple


Benadryl tends to play well with others, but I would ask your OB and your pharmacist (and make sure your pharmacist knows you're pregnant.)
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#3 VAL

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Posted 15 July 2009 - 08:11 PM

I used to take it together and I was at 200mg of traz. I used the children's benadryl because I could control the dose better...just drank little amounts until I was sleepy and my symptoms were better. I only took it at night so I'd wake up the next day without congestion and wheezing (I'm asthmatic). However, anytime you have two sedating drugs you have to be careful of getting overly sleepy and I know nothing about pregnancy and the drugs. Definitely go to your pharmacist as he'll be the most knowledgeable about the combo.
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#4 notfred

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Posted 15 July 2009 - 09:26 PM

Benadryl is in the FDA pregnancy category B. It is not expected to be harmful to an unborn baby. Ask your OB/GYN first before taking it.

nf
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#5 Sara E A

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Posted 16 July 2009 - 03:40 PM

I sometimes take benadryl with trazadone to sleep. (50 mg of each) I'm a little paranoid about mixing meds and never even tried it before I was explicitly instructed to do so by a doc. Benadryl is precisely what's in Tylenol PM that makes you sleep. Apparently histamine is a biochemical made by your brain to keep you awake. So, you're going to be SLEEEPY when you take the benadryl. Maybe try and titrate to a point where you get some relief from the allergies but can still function. Probably the liquid suspension would be best for that kind of experimenting. You said that the only thing your OB cleared to take was benadryl, but I didn't see you mention loratadine, which is my favorite re: allergies.
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#6 In_Remission_pineapple

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Posted 17 July 2009 - 11:46 AM

I sometimes take benadryl with trazadone to sleep. (50 mg of each) I'm a little paranoid about mixing meds and never even tried it before I was explicitly instructed to do so by a doc. Benadryl is precisely what's in Tylenol PM that makes you sleep. Apparently histamine is a biochemical made by your brain to keep you awake. So, you're going to be SLEEEPY when you take the benadryl. Maybe try and titrate to a point where you get some relief from the allergies but can still function. Probably the liquid suspension would be best for that kind of experimenting. You said that the only thing your OB cleared to take was benadryl, but I didn't see you mention loratadine, which is my favorite re: allergies.


Thanks everyone for the helpful replies. I'll go out and get the children's liquid benadryl, that way I can take as low a dose as possible. Good idea!!
MY OB knows I take traz and he thinks adding benadryl is ok. He said only Benadryl for allergies, no loratadine. I get the sense with pregnancy that they just want you to take really old medicines, because
that way if something really terrible happened they would know by now. Well prozac's not that old, but as SSRI's go it is old.

Thanks again.


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