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Too Much Weight Loss On Wellbutrin


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#1 In_Remission_jess1662

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Posted 26 January 2010 - 10:21 AM

I've been on Wellbutrin XL (300mg) for six months. My question is about the weight loss. I was carrying an extra 20-25 pounds or so when I started taking it (mostly due to Zoloft). That weight came off pretty easily, which I was very happy about. The problem is that I have not been able to stop losing weight. I have lost 45 pounds now, and am considered underweight on the BMI scale. The weight loss has slowed, but I am still losing 1/2 to 1 pound a week. I try to keep my calorie count high enough, but it is very difficult, since the Wellbutrin has really affected my appetite.

My doctor is suggesting switching medicines, but I don't want to do this because the Wellbutrin has been very effective in handling the anxiety/depression without destroying my sex drive, and I don't want to go on something that will ruin my sex drive and make me gain too much weight again like Zoloft.

Has anyone had a similar situation, that could give me suggestions on how to stop the weight loss and safely put some weight back on?





#2 shiny

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Posted 26 January 2010 - 11:36 AM

You can combine Zoloft and Wellbutrin. Maybe find a balance that doesn't affect sex drive too much and keeps your weight stable.

I had the same problem switching from Z to W, gained 30 lbs on the first, lost 30 on the second.

You're not having any hypomanic symptoms on the Wellbutrin are you? I completely lose my appetite during hypo/mania.
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#3 Wanda

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Posted 26 January 2010 - 02:10 PM

Can you try lowering the dose? I also lose too much weight on 300 mg Wellbutrin XL. It completely kills my appetite. But 150mg is ok. I was on 150mg for almost a year, and I was able to maintain my weight. The 150mg was still effective for depression.
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#4 Anna

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Posted 31 January 2010 - 07:08 PM

Boost, or other nutrition shakes.

Anna
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#5 jook

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Posted 31 January 2010 - 07:30 PM

Eat high calorie food.

I remember years ago when I lost a lot of weight my GP told me to eat at McDonalds.
I'm not joking.

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former rx= Lexapro, Wellbutrin, Effexor, Zoloft, Topamax, Lamictal, Depakote, Lithobid, Trileptal, Gabitril,
Zonegran, Seroquel, Risperdal, Invega, Zyprexa, Abilify, Geodon, Saphris, Ativan, Xanax, Valium, BuSpar,
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#6 Rishka

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Posted 11 April 2010 - 06:22 PM

I'm having a similar problem. I just have no appetite. I probably weighed about 125lbs when I started it, 3 weeks ago, and am now down to 112lbs or so. 13lbs in 3 weeks is a pretty full on change! I'm just on the 150mgs/day (SR), actually it's brand 'Zyban' (that's how you get it in NZ).

Actually, I should note that ALL the side effects that I had were huge this time round (last time round, was on generic bupro sr, living in the states) - anxiety to the point of continual tears, no appetite, the shakes, sweating etc. I've stabilized now, and maybe have just a little insomnia, but the lack of appetite is hanging around as it tends to, but it's seriously NO APPETITE, not just less of one! Eating is now a chore, and I'm a foodie from way back, so its very strange.

I can see why they won't give this stuff to anorexics. Other than shakes and high calorie food... I'd love to know how to get some of my appetite back. I look ridiculous in all my clothes now!
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#7 Anna

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Posted 11 April 2010 - 08:37 PM

Some meds do impact metabolism ridiculously. If you are having continued problems, and don't want to switch meds consult a nutritionist they are the experts and can track your weight and tailor a food plan for you.

Anna
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Anna

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#8 creepy

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Posted 11 April 2010 - 09:18 PM

wb killed my appetite for all of 2 days before it came back with a vengeance. Wish I knew why that was =(
I want to go back on it. I had good motivation on wb.
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#9 Atticus

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Posted 30 December 2012 - 05:45 PM

I hope it is ok to revive this thread.

I've been on generic Wellbutrin XL 300 two months, and I was on 150 for a monthish before that. It is working well along side my other meds. And I'm really not willing to give it up.

In that time I've dropped two pant sizes, and lost about 20 pounds. We'll call those the remeron/effexor pounds. I could stand to lose another ten, but I don't want to go much below that. As such, I'm wonder whether anyone has had success in stopping the weight loss.

My pdoc is just learning the ropes, and I've had some trouble convincing her that weight loss is a side effect of wellbutrin...so I though I'd try here for some ideas.
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Current: 50 Seroquel, 40 Prozac, 300 Wellbutrin, 900 gabapentin.

Advair 250, nasonex

Former members of the cocktail: Effexor, Trazedone, Lexapro, Buspar (ha), Remeron,

 

I used a light box for about 12 years. It worked. Now I live some place with winter light, and I still need a light box.

 

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#10 martasi2

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Posted 30 December 2012 - 06:01 PM

In that time I've dropped two pant sizes, and lost about 20 pounds. We'll call those the remeron/effexor pounds. I could stand to lose another ten, but I don't want to go much below that. As such, I'm wonder whether anyone has had success in stopping the weight loss.

My pdoc is just learning the ropes, and I've had some trouble convincing her that weight loss is a side effect of wellbutrin...so I though I'd try here for some ideas.


Yes, it's a good idea to revive old threads. So no problem there.

If you express concerns about weight loss then your PDoc is most likely responding to those concerns. So she's being responsible. If the Wellbutrin is suppressing your appetite to the point that you're not eating adequate nutrition or to where your weight loss is noticeable to your PDoc (and she believes it's excessive), that's important too. So I think you have to clarify for her your weight gain/loss history related to the ADs you've taken.
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#11 fairymonkey

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Posted 07 January 2013 - 10:30 AM

This may sound rude but I wish I lost that much weight on Wellbutrin. Sigh.
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My actual diagnosis: It's still a debate. Psychologists can't seem to diagnose me. Post Traumatic Stress Disorder w/ Depression and anxiety. co-dependency issues.
Past meds: Effexor, Lexapro, Fluoxetine , Bupropion XL ,Klonopin, Ativan, Nortriptyline ,Remeron
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“Sometimes fate is like a small sand-storm that keeps changing directions. You change direction, but the sand-storm chases you. You turn again, but the storm adjusts. Over and over you play this out, like some ominous dance with death just before death. Why? Because this storm isn't something that has nothing to do with you. This storm is you.”
Haruki Murakami, Kafka on the Shore

#12 Atticus

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Posted 07 January 2013 - 11:26 AM

Not rude at all, Fairymonkey. I totally get that.

I am pleased to say that after consulting with her mentor, the pdoc has agreed that this can be a side effect. So we're going to wait and see if it tails off. In the mean time, I'm tracking what I'm putting in my mouth each day. As this no longer includes every piece of candy in a ten mile radius...
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Current: 50 Seroquel, 40 Prozac, 300 Wellbutrin, 900 gabapentin.

Advair 250, nasonex

Former members of the cocktail: Effexor, Trazedone, Lexapro, Buspar (ha), Remeron,

 

I used a light box for about 12 years. It worked. Now I live some place with winter light, and I still need a light box.

 

This is imperfect.


#13 fairymonkey

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Posted 07 January 2013 - 11:39 AM

Great thing I didn't get a bad response. But gaining about 40 pounds on Prozac/Remeron has made me extremely angry haha. Do you have insurance to so a nutritionist? You cannot simply eat fatty food all the time.
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My actual diagnosis: It's still a debate. Psychologists can't seem to diagnose me. Post Traumatic Stress Disorder w/ Depression and anxiety. co-dependency issues.
Past meds: Effexor, Lexapro, Fluoxetine , Bupropion XL ,Klonopin, Ativan, Nortriptyline ,Remeron
Supplements: Melatonin
Diet: Strictly Vegetarian

“Sometimes fate is like a small sand-storm that keeps changing directions. You change direction, but the sand-storm chases you. You turn again, but the storm adjusts. Over and over you play this out, like some ominous dance with death just before death. Why? Because this storm isn't something that has nothing to do with you. This storm is you.”
Haruki Murakami, Kafka on the Shore

#14 tamagotchi

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Posted 07 January 2013 - 04:13 PM

Atticus, of course weight loss can be a side effect but I wouldn't worry about it unless you become seriously underweight. I lost almost 50 lbs and was starting to worry, but then my weight stabilized within the normal BMI range. And then the appetite came back and now I'm fighting weight gain.
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#15 feelin_happy

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Posted 13 June 2013 - 02:25 PM

I'm hoping I have similar results as others here on this tread... I was originally on generic Celexa for anxiety and depression, and started putting on weight at an alarming rate. It was close to 1.5 lbs a week -- after having a steady weight for a decade! My gp gradually had me come off of the Celexa and replaced with Wellbutrin. I've been on it for about a month, and am hoping the weight starts to go away soon...


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#16 kala878

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Posted 06 July 2013 - 07:52 PM

Haha..weight loss is a nice side effect of Wellbutrin, but the weird head feeling isn't :huh: . My head feels odd and my mood is, quite frankly, #itchy :evil: .  I don't want to gain weight by going back on Celexa, but i just might have to do that. Even my hubby doesn't like how i am on this med :huh:  I've been on wellbutrin for almost a month now. i can tell it has really affected my appitite.  I've been on zoloft, lexapro, celexa..  I lost weight at first with celexa, then when i needed a higher dose, it made me gain weight. I'm a plus size/curvy girl anyways and don't mind a few extra lbs, but 40 is bad.


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#17 Elisabet_Fluffy

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Posted 04 September 2013 - 12:43 PM

I'm on Wellbutrin and I lost a bunch of weight.  I'm about 5'6'' and last week I was weighed at the doctor's office and was 112 lbs.  I'm sure that I'm a bit more now, as that was when I had an upset stomach and even if I tried to eat it wouldn't stay in.  I also KNOW that I have a bunch of poop in my colon that is probably weighing me down, as all of my meds have constipation as a side effect.  Anyway, I used to be in the 140-150 range.  I have a medium/kind of large frame, and probably anything under 130 would be considered underweight for me. 

 

Still, I kind of want Wellbutrin to make me lose even more weight.  I told my psychiatrist that I tend towards thoughts and sometimes behaviors that make me very susceptible to developing an eating disorder, but she didn't seem to give a shit and perscribed it anyway.  That's probably bad, right?

 

Anyway, go for high-calorie density foods, so you at least don't have to put forth a lot of time and energy with it.  Are there any sort of junky foods that you like enough to not need to be hungry to eat?  Not absolute crap, but maybe ice cream or dark chocolate or something?  Building muscle could also be good.


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My diagnosis is almost definitely not correct, or at least not complete.  I am probably bipolar, and my myoclonus may have a cause that the neurologist simply hasn't figured out.


#18 crzeepilz

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Posted 11 September 2013 - 05:34 PM

Well I am brand new to this forum and man its helpful. I have probably gained about 20llbs on effexor which is why I am switching over to wellbutrin.   I only started it 2 days ago and stopped my effexor cold turkey. Bad idea. My doc sucks and I had no idea how sick I would get. 

I am about 5'6" with a mediumframe and weigh 157.  I am so unhappy with the weight gain but the worst part is ; I am an athlete who trains 5-6 times a week and can't lose a pound. Sadly I am praying wellbutrin helps with this. 


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#19 irisstars

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Posted 17 September 2013 - 12:18 AM

Brand new to this forum.... i just started using this drug as well for smoking and i am also on the patch..i do as well don't feel like i need to over eat...Bring IT on the weight loss!!! i was very upset now im not its been a week


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#20 Swerly85

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Posted 31 May 2015 - 09:37 PM

So I'm going to revive this thread once again.
I was on Zoloft previously but it totally took away my sex drive and that was NO good. I therefore switched to Wellbutrin. I'm noticing some weight loss, and I'm not complaining. But what is the problem is that I'm highly anxious. Much more than I ever was before. My LCSW (who recommended I take antidepressants) told me that I should speak to my primary physician to change the medication.
But I don't want to be on anything that will alter my sex drive. And I'm enjoying the weight loss.
Anyone dealt with this in the past?
To summarize: Zoloft caused NO sex drive. Wellbutrin is causing crazy anxiety. I'm enjoying wellbutrins weight loss. Need suggestions due to experience.
Thank you.
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#21 Irreal_Mentality

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Posted 02 June 2015 - 09:11 AM

So I'm going to revive this thread once again.
I was on Zoloft previously but it totally took away my sex drive and that was NO good. I therefore switched to Wellbutrin. I'm noticing some weight loss, and I'm not complaining. But what is the problem is that I'm highly anxious. Much more than I ever was before. My LCSW (who recommended I take antidepressants) told me that I should speak to my primary physician to change the medication.
But I don't want to be on anything that will alter my sex drive. And I'm enjoying the weight loss.
Anyone dealt with this in the past?
To summarize: Zoloft caused NO sex drive. Wellbutrin is causing crazy anxiety. I'm enjoying wellbutrins weight loss. Need suggestions due to experience.
Thank you.

 

Edit: the following suggestions apply if you do decide to stay on the bupropion.  If it's working well for you it might be better to try and deal with the anxiety itself, rather than switching so quickly to another medication.  I don't have firsthand experience with this as I haven't tried to go back on bupropion, but I have heard that, like a handful of meds, it may not work as well the second time.

 

When I was on bupropion SR the anxiety was very intense; I know exactly what you're referring to.  My Pdoc mentioned that sometimes controlling the physical symptoms of anxiety can help greatly with the anxious thoughts as a whole, since anxiety is often kind of a feedback loop.  How are your anxious symptoms physically manifesting?  I personally had a lot of nausea, headaches from jaw tension, and a racing heartbeat, so I went through a lot of antacid, ibuprofen and Excedrin.  If it's highly physical (racing heart, sweating, dizziness, etc.) you might want to talk to your Pdoc about possibly adding a beta-blocker like propranolol, which can be taken as-needed during anxiety attacks (which is how I still use it), or daily if you feel like you're constantly on edge.  Adding another psych/crazy med to deal with the anxiety is also an option that might work for you, but when I was on bupropion, both meds I tried specifically for anxiety didn't pan out, so I was left with mainly cognitive and physiological options for managing it.

 

The other suggestion I have would be to look at the release formulation you're on.  Is it XL, SR, IR?  This is pure conjecture on my part, but if you're on IR (which releases the bupropion quickly, almost all at once) or SR (which releases it more gradually over a somewhat longer period of time, ~6 hours IIRC), you might want to consider switching to eXtended reLease, which gives you a steadier dose released very slowly over the course of an entire day.  I imagine that having too fast of a release mechanism could definitely exacerbate anxiety.


Edited by Irreal_Mentality, 02 June 2015 - 09:14 AM.

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Past Meds: Bupropion SR (various dosages, starting at 100 mg/daily and increasing to 300 mg in two daily doses; sent my anxiety through the roof, worked fine for depression symptoms for a couple months, gradually pooped out, didn't work very well at higher doses and really didn't agree with me insofar as side effects), Buspirone (10 mg/daily; gave me the worst nightmares I've ever had in addition to a bizarre, horrifying, and very atypical nearly psychotic anxiety attack), Gabapentin (100 mg/daily; cognitive impairment was too pronounced, made me a ditz), Propranolol (10 mg/daily; lowered my blood pressure too much taking it every day), Pramipexole (0.125 mg/dailymade me an anxious edgy caricature of BP II for a month, and way too irritable)

 

Current supplements: Vitamin D (5000 IU 1x/daily), L-arginine (1 g/~3x/daily)

 

"You can hold yourself back from the sufferings of the world, that is something you are free to do and it accords with your nature, but perhaps this very holding back is the one suffering you could avoid."

 

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                                                                   --Franz Kafka

 

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