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Luvox And Smoking?


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13 replies to this topic

#1 In_Remission_mike104

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Posted 11 May 2010 - 06:36 PM

This is my first night on Luvox, popped a pill of 50mg a few hours ago. I have read that smoking decreases the effect of the drug, but as a typical smoker, I ignored it.

So right now I lit a cigarette, and I couldn't finish it. It tasted horrible to me. Does Luvox also affect the pleasure you get from smoking?

Also, is it really a big deal if I continue to smoke? I know it is a bad and unhealthy habit but I'm not ready right now to quit this addiction.





#2 Deep Sea Philosopher

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Posted 12 May 2010 - 05:04 PM

Luvox did not have an influence on my smoking. I did quit a few weeks ago, but that was mainly due to the concerns of the interaction.
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#3 In_Remission_sad

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Posted 17 May 2010 - 02:16 PM

Luvox did not have an influence on my smoking. I did quit a few weeks ago, but that was mainly due to the concerns of the interaction.



#4 In_Remission_sad

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Posted 17 May 2010 - 02:19 PM

This is my first night on Luvox, popped a pill of 50mg a few hours ago. I have read that smoking decreases the effect of the drug, but as a typical smoker, I ignored it.

So right now I lit a cigarette, and I couldn't finish it. It tasted horrible to me. Does Luvox also affect the pleasure you get from smoking?

Also, is it really a big deal if I continue to smoke? I know it is a bad and unhealthy habit but I'm not ready right now to quit this addiction.



smoking isn't as unhealthy as luvox

#5 Deep Sea Philosopher

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Posted 17 May 2010 - 02:38 PM

This is my first night on Luvox, popped a pill of 50mg a few hours ago. I have read that smoking decreases the effect of the drug, but as a typical smoker, I ignored it.

So right now I lit a cigarette, and I couldn't finish it. It tasted horrible to me. Does Luvox also affect the pleasure you get from smoking?

Also, is it really a big deal if I continue to smoke? I know it is a bad and unhealthy habit but I'm not ready right now to quit this addiction.



smoking isn't as unhealthy as luvox


How is smoking healthier than Luvox?!
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My Kind of Crazy: Schizoaffective Disorder of the Bipolar Type

Meds: 30mg Dexedrine Spansule .. 200mg Lamictal .. 80mg Latuda .. 600mg Neurontin .. 200mg Ultram ER

Some people say the grass is always greener on the other side.
I say be the gardener. Water it. Feed it. Make your own grass grow.
I make the grass greener wherever I am. I'm the gardener.

#6 In_Remission_mike104

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Posted 20 May 2010 - 06:03 PM

This is my first night on Luvox, popped a pill of 50mg a few hours ago. I have read that smoking decreases the effect of the drug, but as a typical smoker, I ignored it.

So right now I lit a cigarette, and I couldn't finish it. It tasted horrible to me. Does Luvox also affect the pleasure you get from smoking?

Also, is it really a big deal if I continue to smoke? I know it is a bad and unhealthy habit but I'm not ready right now to quit this addiction.



smoking isn't as unhealthy as luvox


why is luvox unhealthy?

#7 Jerod Poore

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Posted 02 June 2010 - 12:00 PM

This is my first night on Luvox, popped a pill of 50mg a few hours ago. I have read that smoking decreases the effect of the drug, but as a typical smoker, I ignored it.

So right now I lit a cigarette, and I couldn't finish it. It tasted horrible to me. Does Luvox also affect the pleasure you get from smoking?


While smoking affects Luvox, I can't find a damn thing about Luvox affecting smoking, other than the usual incidents of mixing two drugs that mess around with neurotransmitters and receptors. Especially two drugs that affect the same conditions. Taste perversion is a known, albeit infrequent side effect of Luvox, so it might be that.

Also, is it really a big deal if I continue to smoke? I know it is a bad and unhealthy habit but I'm not ready right now to quit this addiction.


Because smoking increases the clearance of Luvox by 25-30%, quitting cold turkey isn't a good idea. So it's not a big deal to continue smoking as far as Luvox is concerned, just work with the doctor who prescribes the Luvox and quit by reducing the amount you smoke and/or use a patch or gum.
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#8 Jerod Poore

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Posted 02 June 2010 - 12:05 PM

I was on Luvox for about three months, and I couldn't finish my second cigarette without feeling like I was gonna puke. Normally I can smoke a couple cigs and feel great, but when I Luvox made smoking so unpleasant.


If Luvox were like Paxil when it came to discontinuation syndrome I'd guess it was the second cigarette causing you to have too little Luvox that was making you sick. While Luvox isn't like that, it's the only SSRI with a half-life that's less than a day (~15 hours). That's still a longshot.
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Jerod Poore - Owner, Founder and Chief Citizen Medical Expert of crazymeds.us
I am not a doctor, nor do I play one on TV. No doctor, nurse, pharmacist or lawyer was harmed in the creation of this post. No warranty is expressed or implied. Not valid with any other offer. Void where prohibited.

Current meds: lamotrigine 200mg, topiramate 400mg, buspirone 60mg, protriptyline 60mg, EPA 600mg, lorazepam 1mg PRN
Past meds (likely incomplete): Abilify, clonazepam, desipramine, diazepam, Gabitril, lithium, methylphenidate, Neurontin, Paxil, prochlorperazine, Provigil, Prozac, Risperdal, Seroquel, Serzone, Strattera, Trileptal, Zyprexa

#9 Jerod Poore

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Posted 02 June 2010 - 12:07 PM

smoking isn't as unhealthy as luvox


I'm Big Tobacco's biggest enabler, but that statement is utter bullshit.
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Jerod Poore - Owner, Founder and Chief Citizen Medical Expert of crazymeds.us
I am not a doctor, nor do I play one on TV. No doctor, nurse, pharmacist or lawyer was harmed in the creation of this post. No warranty is expressed or implied. Not valid with any other offer. Void where prohibited.

Current meds: lamotrigine 200mg, topiramate 400mg, buspirone 60mg, protriptyline 60mg, EPA 600mg, lorazepam 1mg PRN
Past meds (likely incomplete): Abilify, clonazepam, desipramine, diazepam, Gabitril, lithium, methylphenidate, Neurontin, Paxil, prochlorperazine, Provigil, Prozac, Risperdal, Seroquel, Serzone, Strattera, Trileptal, Zyprexa

#10 wynand32

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Posted 01 December 2012 - 08:27 AM

I'm resurrecting an old thread here, but I've gotten a bit confused about the whole smoking/nicotine vs. Luvox question. Basically, most information I've seen is that it's certain hydrocarbons in cigarette smoke that cause the problems with Luvox, not the nicotine. But, I've read a few references that say it's the nicotine. Can anyone clarify?
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#11 mfortunato

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Posted 01 July 2014 - 03:26 PM

i would like to know this too wynand32. if i should switch to eletronic cigs to get a better reaction to the meds
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#12 egodystonic_James

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Posted 19 January 2015 - 05:56 PM

I'm resurrecting an old thread here, but I've gotten a bit confused about the whole smoking/nicotine vs. Luvox question. Basically, most information I've seen is that it's certain hydrocarbons in cigarette smoke that cause the problems with Luvox, not the nicotine. But, I've read a few references that say it's the nicotine. Can anyone clarify?

 

I have wondered the same thing. Is the interaction with Luvox due to the hydrocarbons from the actual smoke, or is it actually interacting with nicotine? If someone can help me with this question, I would greatly appreciate it. I do not smoke anymore but use a nicotine vaporizer - electronic cigarette. I really want to go back on Luvox and I just want to know if I should start at a larger dose to compensate what is "lost" from the nicotine use.

 

James


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Diagnoses

-Bipolar 2 (in partial remission)(mostly depressed phase)

-Somatoform Pain Disorder

-Cotard Delusion (in partial remission)(No longer in the DSM, but I sure as hell have it and have been dx'd with it)

 
Meds

Lamictal (brand lamotrigine) 200 mg twice daily

Latuda (brand lurasidone) 120 mg once daily with dinner

Topamax (generic topiramate) 100 mg twice daily

Buspar (generic buspirone hcl) 15 mg four times daily

trazodone  (generic) 150 mg once daily at bedtime

 

Additional meds

-Lpitor (brand atorvastatin) 20 mg daily

-Vitamin D 5000 IU

-Folic Acid 400 mcg

 

 

*****Crazymeds is such a beneficial piece of my life. Much props to Jerod for making it possible *****

 

                                                   


#13 fk80

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Posted 29 March 2015 - 04:46 PM

Fluvoxamine is a strong inhibitor and substrate of the CYP1A2 enzyme. The polyaromatic hydrocarbons in cigarette smoke are a CYP1A2 inducer, resulting in an increased output of the enzyme. More enzyme means faster metabolism and faster clearance of the drug.
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Dx: BP II, MDD, GAD / PD, PTSD, low testosterone

 

Current Rx: lamotrigine (200 mg PM), clonazepam (0.5 mg/day), gabapentin (600 mg for sleep), testosterone gel (1%; no significant total or free T increase after 3 months)

Supplements: NAC (600 mg tid), vitamin b-complex, vitamin D3 (2000 IU), lutein (20 mg; to see if it benefits vision problems from lamotrigine)

Other: doxylamine (25 mg for sleep), fluticasone (for allergies)

Previous Rx: Parnate (up to 60 mg for 1 year), Marplan (intolerable side effects), Nardil (tried twice; last dose at 75 mg led to mixed state, weight gain), Latuda (no noticeable benefit, caused RLS), Lexapro (great for anxiety/PD, but no help for depression; caused apathy and emotional numbing), T3 (no benefit), Abilify (helpful for motivation, but pdoc at the time took me off of it), Adderall XR (helpful for motivation, but built up some tolerance and pdoc removed it from regimen), Strattera (only helped for several weeks before tachyphylaxis set in), Wellbutrin SR & XL (regular version and these both either stopped working or didn't work), risperidone (tried for irritability/agitation, no help, couldn't tolerate side effects), propranolol (not enough benefit to continue use), mirtazapine (intolerable side effects), Xanax (worked great years ago; pdoc switched to klonopin), Zoloft (didn't take long enough to notice effect), Cymbalta (can't remember much about this, but I think side effects weren't tolerable and didn't see much benefit), Serzone (seemed to help when I took it; prescribed by GP so he changed meds instead of upping dose), Effexor XR (insomnia and hypomania), Paxil (can't remember, don't want to try due to weight gain issues), Prozac (no benefit), Luvox (no benefit), Librium, BuSpar (too drowsy), Ativan (can't remember), Lithobid (zombified), Synthroid (hypothyroidism due to lithium)


#14 egodystonic_James

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Posted 29 March 2015 - 05:52 PM

Nice to know ;).

 

James


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Diagnoses

-Bipolar 2 (in partial remission)(mostly depressed phase)

-Somatoform Pain Disorder

-Cotard Delusion (in partial remission)(No longer in the DSM, but I sure as hell have it and have been dx'd with it)

 
Meds

Lamictal (brand lamotrigine) 200 mg twice daily

Latuda (brand lurasidone) 120 mg once daily with dinner

Topamax (generic topiramate) 100 mg twice daily

Buspar (generic buspirone hcl) 15 mg four times daily

trazodone  (generic) 150 mg once daily at bedtime

 

Additional meds

-Lpitor (brand atorvastatin) 20 mg daily

-Vitamin D 5000 IU

-Folic Acid 400 mcg

 

 

*****Crazymeds is such a beneficial piece of my life. Much props to Jerod for making it possible *****

 

                                                   



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