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Clonazepam


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18 replies to this topic

#1 In_Remission_catn!p23

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Posted 30 March 2010 - 06:42 PM

I just wanted to speak up in favor of Klonopin brand clonazepam. Yep. After spending over a year on generics, the third time the pharmacy wanted to change the GENERIC (!) I just asked for brand-name. The insurance only covers a percentage of it, so it costs more, but the difference is worth it, for me.

It's frustrating enough knowing that your generic drug might not be the same formula/potency/mf'g process as the 'real thing'...toss in the fact that a pharmacy wants to stay with whoever's the lowest-cost vendor to them...they can switch your generics at the drop of a hat...grr...
Anyway, for me, I prefer the consistency in quality and reliability of the big K. Just sayin'.



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#2 A PirateSaysARRRRR

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Posted 30 March 2010 - 08:05 PM

Well, good thing I've never had the brand name then I guess. I recently switched generics and think my new ones are a little different.

I was using Teva brand, now I'm using Mylan, but maybe it's just my imagination. SOMETHING is making me more tired.

I'd like to try the brand name, I guess, but it's more expensive than the real thing. I wish there was more regulation as to how much of the active ingredient actually goes into the product.

But, like I said ,I've never had the real thing, so it makes no difference to me, as long as they keep the anxiety under control.
  • 0
DX: GAD, Social Phobia, Panic Disorder, some kind of "mood issues" apparently.
RX: Lamictal 150mg, diazepam 10mg 3x per day, Abilify 15mg

Shit that didn't work: Sertrailne, Buspirone, Mirtazipine, Gabapentin, Paroxetine, Effexor XR, Lorazepam, Cymbalta, Zolpidem, Bpropion XL, Pristiq, fluoxetine, clonazepam

________________________________________


And I swear I left my sanity someplace in this mess
crumpled between empty beers and packs of ciagarettes

#3 Anna

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Posted 02 April 2010 - 04:29 AM

As a general rule, if you've never had brand, start with generic. It's cheaper for everyone, including society. Hey, we are supposedly entering "socialized" medicine. There are a few meds, very few, such as WB, that might be an exception to this rule.

If you find a generic you like, work with the pharmacy (as a rule, smarller pharms are better at doing this) to TRY and get them to give you consistently the same generic. Especially for things like seizure control.

There has, as Serpens has noted, been WAY too much generic bashing lately. It's ridiculous.

I must note that, in my personal experience, I take generics on everything I can, don't worry if the generic changes, and am fine. I must not be that special a snowflake, but I don't psych myself out over generics and they all seem to work fine for me. But then again, I don't really want to be any more of a special snowflake than I already am.

Again, for seizure control issues or rapid cycling (which I don't do) there may be exceptions to this.

Please don't raise my insurance rates unless you have to! My kid was just dx with allergies and asthma and that little episode cost me like $350 in copays alone so far and he's not stable yet, so god only knows....

Anna
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Anna

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#4 In_Remission_catn!p23

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Posted 07 April 2010 - 01:20 PM

I'm not here to "bash" generic drugs...sure, some of them are fine for me, too. But even right here on this site it's noted that there is, for some reason, a marked difference between Klonopin brand clonazepam and <i>most</i> generic forms of that particular medicine. And I'm just raising my hand to say, yeah, I find that to be true in my personal experience as well...so if there are a bunch of other people out there who think they're "saving money" on generic clonazepam, they may be also fooling themselves into settling for less than 100% effectiveness of the drug. It is that big of a difference. If right now you just have "absence of anxiety" maybe you could have "optimistic feelings". sound good?

Generic drugs can have anywhere between 80% to 125% bioavailability, and I'm pretty sure even THAT varies from individual to individual, depending on one or another's biochemistry, etc.

If a person takes generic drugs for absolutely everything, and has never taken a brand-name drug....simply put, how would one know the difference in effectiveness, if there is one, unless there was just no relief at all from a symptom?

I'm over all this, "I ain't special. generic's good enough fer good ol' me." ad nauseum as well when people could just as easily say, "I'd rather spend the money on cigarettes/lottery tickets/movies/beer than brand-name prescriptions."

#5 A PirateSaysARRRRR

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Posted 07 April 2010 - 03:17 PM

I'd rather spend money on cigarettes, beer, and strippers than brand name prescriptions.

I've never had a brand name. I take clonazepam and have taken two generics, they both work. I take AD's to feel optimistic, generic AD's because I'm poor and I DO need the above mentioned things. These drugs help me well enough and it DOES sound like you are bashing generic drugs.

Yeah, it sucks that the FDA doesn't step up and make sure that all generics contain the same active ingredient as the name brand. Money is the reason anyway, as you can imagine. Of course it's cheaper to buy someting that has LESS of the active ingredient in it. I think pharmaceutical companies and the FDA can kiss my ass, unfortunately, I need their drugs to remain sane.

I'm not special, generic IS good enough for me, assuming it WORKS, when it doesn't work, even name brand isn't good enough for me.
  • 0
DX: GAD, Social Phobia, Panic Disorder, some kind of "mood issues" apparently.
RX: Lamictal 150mg, diazepam 10mg 3x per day, Abilify 15mg

Shit that didn't work: Sertrailne, Buspirone, Mirtazipine, Gabapentin, Paroxetine, Effexor XR, Lorazepam, Cymbalta, Zolpidem, Bpropion XL, Pristiq, fluoxetine, clonazepam

________________________________________


And I swear I left my sanity someplace in this mess
crumpled between empty beers and packs of ciagarettes

#6 want2Bfree

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Posted 15 April 2010 - 04:13 PM

Another reason people may receive the generic version of their prescription is because pharmacies make money off of generics. I take generics for everything except for Carbatrol, and that's probably only because Carbatrol doesn't have a generic out yet, and isn't marketed to have one until 2011.

Edited by want2Bfree, 15 April 2010 - 04:14 PM.

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Past Rx: Zoloft, Prozac, Lexapro, Lamictal, Ativan, Abilify, Provigil, Geodon, Trileptal, Carbatrol (and there are probably some I am missing/forgetting.)

#7 Anna

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Posted 16 April 2010 - 11:51 AM

That's why keeping the small chains in business is such a great plan. They may be willing to keep you on one generic. That's the best option, most likely. It's the switching that is causing the problem.

We could lobby the FDA to seek generic-regulation but I see some MAJOR problems with that.

Obviously, use your personal choice to buy what you want but I must note as a socialist of some time (husband is conservative, don't worry, you won't hurt my feelings) that yes, refusal of generics does impact me.

Anna
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Anna

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#8 therapeuticbrigg84

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Posted 16 April 2010 - 12:10 PM

Well, good thing I've never had the brand name then I guess. I recently switched generics and think my new ones are a little different.

I was using Teva brand, now I'm using Mylan, but maybe it's just my imagination. SOMETHING is making me more tired.

I'd like to try the brand name, I guess, but it's more expensive than the real thing. I wish there was more regulation as to how much of the active ingredient actually goes into the product.

But, like I said ,I've never had the real thing, so it makes no difference to me, as long as they keep the anxiety under control.

I've tried mylan and the same thing happened with me, so now i stick with teva, but just recently i got the brand name kind for onlyyyy $25.

dx: schizotypal personality disorder, dystonic neck and back pain, GERD. a bit of TD, akathisia, dysmorphic thoughts, affect is questionable

seroquel and inderal 60mg made me fatigued/ depressed. may hafta try lopressor or bisoprolol

inderal interacts with ssris and anti-psychs.

success HCTZ not only lowers my blood pressure and pulse more effectively. but it also has helped with the headaches ive been having. i should see a doctor about this.

[color="#0000FF"]rx: klonopin .5-1 prn, omega 3 fish oil, vitamin D3 iu, albuterol sulfate inhaler, magnesium hydroxide(for the constipationg)

in flux: seroquel 50mg
up and coming: nuvigil

looking into injectables.


artane 2 mg PRN(rare), trazodone 50mg PRN, lyrica PRN?


#9 bergsonisme

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Posted 16 April 2010 - 12:48 PM

Roche's brand-name clonazepam (they call it Rivotril) is so cheap here generic brands went out of the market. It also made the overall list of top-prescribed drugs last year, second only to //@lipitor//, IIRC.
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#10 A PirateSaysARRRRR

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Posted 16 April 2010 - 12:55 PM

Well, good thing I've never had the brand name then I guess. I recently switched generics and think my new ones are a little different.

I was using Teva brand, now I'm using Mylan, but maybe it's just my imagination. SOMETHING is making me more tired.

I'd like to try the brand name, I guess, but it's more expensive than the real thing. I wish there was more regulation as to how much of the active ingredient actually goes into the product.

But, like I said ,I've never had the real thing, so it makes no difference to me, as long as they keep the anxiety under control.

I've tried mylan and the same thing happened with me, so now i stick with teva, but just recently i got the brand name kind for onlyyyy $25.



Yeah, I want to go back to Teva, I don't even think this brand is as effective as the Teva brand!
  • 0
DX: GAD, Social Phobia, Panic Disorder, some kind of "mood issues" apparently.
RX: Lamictal 150mg, diazepam 10mg 3x per day, Abilify 15mg

Shit that didn't work: Sertrailne, Buspirone, Mirtazipine, Gabapentin, Paroxetine, Effexor XR, Lorazepam, Cymbalta, Zolpidem, Bpropion XL, Pristiq, fluoxetine, clonazepam

________________________________________


And I swear I left my sanity someplace in this mess
crumpled between empty beers and packs of ciagarettes

#11 jook

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Posted 16 April 2010 - 04:41 PM

I took brand name Klonopin for years and switched over to Teva generic because of costs.
There is no difference between the two.

jook
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my brain hates agonists and reuptake-inhibitors

former rx= Lexapro, Wellbutrin, Effexor, Zoloft, Topamax, Lamictal, Depakote, Lithobid, Trileptal, Gabitril,
Zonegran, Seroquel, Risperdal, Invega, Zyprexa, Abilify, Geodon, Ativan, Xanax, Valium, BuSpar, Nuvigil
various combinations with all of the above

#12 Serpens

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Posted 16 April 2010 - 05:18 PM

Yeah, it sucks that the FDA doesn't step up and make sure that all generics contain the same active ingredient as the name brand. Money is the reason anyway, as you can imagine. Of course it's cheaper to buy someting that has LESS of the active ingredient in it.


They do. Maintaining the same physical quantity of the drug is one of the easiest things. What is extremely difficult is matching the pharmacodynamic properties within the 90% confidence interval of the reference drug with a manufacturing. Matching a Tmax/Cmax to a plain old tablet can be somewhat problematic, even if you know the on paper composition of that tablet. If you start messing with controlled release systems it becomes blathering insane. Exact duplication of a patent protected controlled release technology with a confidential or protected manufacturing process is on the verge of totally impossible.



That's why keeping the small chains in business is such a great plan. They may be willing to keep you on one generic. That's the best option, most likely. It's the switching that is causing the problem.


Behold, the consensus of every significant paper written on therapeutic nonequivalence within the last twenty five years. Small/small chains have other issues though.

We could lobby the FDA to seek generic-regulation but I see some MAJOR problems with that.


Every pharmacy, tech, PBM and pharmacist in the country would simultaneously commit suicide. Enforceable therapeutic continuity on generic medications? The shipping problems, the rejections, the NDC issues, god forbid the repackaging (or worse the drug repackagers), the backorders. It's better being done on a case by case basis.
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#13 roxyhead

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Posted 30 April 2010 - 03:34 PM

Roche's brand-name clonazepam (they call it Rivotril) is so cheap here generic brands went out of the market. It also made the overall list of top-prescribed drugs last year, second only to //@lipitor//, IIRC.


I can't say I've ever seen that on a shelf here, but it's what I've heard a Canadian doctor refer to it as, it may be available if you have it ordered in. I do that with brand name Roche Valium, so few people use that one, either (Apotex diazepam doesn't work as a muscle relaxant), and it's pretty cheap, too. The generic companies here are pretty good at getting their copy in for stuff a lot of people use, it seems like these days the only things there aren't generics of as soon as possible are puffers (maybe the HFA switch screwed things up with patents? Though generic HFA Ventolin's cheap and readily available...hmm.), birth control pills, and my bloody Dexedrine, which has been around forever yet still runs me about 90 cents for a 10mg pill...nothing that can compete with generics by being cheap.
  • 0

I'm not new, I just post less often than the board changes servers. I guess I'm a "C and E" of these boards, I only show up for med changes. So sue me.

Even *I* just call them brain cooties...
(ADHD inattentive, evil headaches NOS (Local marching band and jackhammer squadron, with a bit of Chinese opera thrown in), occasional SAD, suspected simple partial seizures of a suspected temporal lobe variety, ABD IBS)

Asperger's Control Group - MMR vaccine before 1yr, was normal til about 2. Put that in your pipe and smoke it, vax people. Second shot at 10 and didn't get worse.

Ex-meds: Amitriptyline, Maxalt, Relpax, Ritalin/SR, clonazepam, Flexeril, Risperdal, Celexa, Wellbutrin, Effexor, and a whole load of non-psych/headache stuff. Still use Valium and Ativan PRN, trying metoclopramide/aspirin now, too. May try clonidine again.

Cocktail of the day: "I'm With Stupid" - Keppra + Topamax (sorry, not available in liquid, but the taste alone would probably kill you...splitting both pills is bad enough!)


#14 therapeuticbrigg84

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Posted 30 April 2010 - 07:59 PM

oh and then there's the klonopin wafers, which i haven't tried, i dont even remember the last time i heard of those

Edited by therapeuticbrigg84, 30 April 2010 - 08:00 PM.

dx: schizotypal personality disorder, dystonic neck and back pain, GERD. a bit of TD, akathisia, dysmorphic thoughts, affect is questionable

seroquel and inderal 60mg made me fatigued/ depressed. may hafta try lopressor or bisoprolol

inderal interacts with ssris and anti-psychs.

success HCTZ not only lowers my blood pressure and pulse more effectively. but it also has helped with the headaches ive been having. i should see a doctor about this.

[color="#0000FF"]rx: klonopin .5-1 prn, omega 3 fish oil, vitamin D3 iu, albuterol sulfate inhaler, magnesium hydroxide(for the constipationg)

in flux: seroquel 50mg
up and coming: nuvigil

looking into injectables.


artane 2 mg PRN(rare), trazodone 50mg PRN, lyrica PRN?


#15 Classically_James

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Posted 01 May 2010 - 07:32 PM

OMG, Klonopin wafers are the yummiest!!!! For a brief instant after I put them in my mouth, they tasted like bubble gum and buttered popcorn. The last time I had some was 2005. I don't know if they make them anymore.....the whole point of them, as I understand, was to make the normally slow-onset of action of clonazapam faster so the Klonopin can compete with the quicker-acting benzos like Xanax (alprazolam) or Valium (diazepam).

James
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Diagnoses:

1. Major Depressive Disorder (MDD - atypical type)

2. Seasonal Affective Disorder (SAD)

3. Borderline Personality Disorder (BPD)(in partial remission)

4. Cotard's Delusion (removed prior to DSM IV in 1994(in partial remission)  

 

Medications:

1 Cymbalta 60 mg

2. Abilify 10 ng

3. Soma 350 mg TID

4. Lunesta 3 mg

5. Forfivo XL 450 mg


#16 therapeuticbrigg84

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Posted 01 May 2010 - 08:50 PM

hahah lol valium isnt that mcuh quicker acting than kpin right though? i think ativan is quicker acting than valium

dx: schizotypal personality disorder, dystonic neck and back pain, GERD. a bit of TD, akathisia, dysmorphic thoughts, affect is questionable

seroquel and inderal 60mg made me fatigued/ depressed. may hafta try lopressor or bisoprolol

inderal interacts with ssris and anti-psychs.

success HCTZ not only lowers my blood pressure and pulse more effectively. but it also has helped with the headaches ive been having. i should see a doctor about this.

[color="#0000FF"]rx: klonopin .5-1 prn, omega 3 fish oil, vitamin D3 iu, albuterol sulfate inhaler, magnesium hydroxide(for the constipationg)

in flux: seroquel 50mg
up and coming: nuvigil

looking into injectables.


artane 2 mg PRN(rare), trazodone 50mg PRN, lyrica PRN?


#17 Anna

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Posted 02 May 2010 - 07:05 AM

Every pharmacy, tech, PBM and pharmacist in the country would simultaneously commit suicide. Enforceable therapeutic continuity on generic medications? The shipping problems, the rejections, the NDC issues, god forbid the repackaging (or worse the drug repackagers), the backorders. It's better being done on a case by case basis.


Heh yeah. They'd hate us.

That's why I agree, it's better to go with the small chain, but only if you can find a GOOD one that will do what you want. They are out there, but it will mean developing a "relationship" with your pharmacist.

Get your minds out of the gutter :mad:

Otherwise, if there is significant response diffference, using brand will be easiest, but more expensive, probably.

My new (non SMI public doctor, just switched out of the system) is all about putting me on brand depakote ER next visit, I think. Fine, because I have cadillac health insurance, due to working for the government.... He says it's better and I'm like, whatever, dude, fine. But then again, I don't worry too much about the generics.... I take generic risperdal, depkote, and neurontin at the moment.

When I'm stable, it doesn't bother me too much, usually. I'm not that sensitive to most things.... The only problem I ever had was with WB, but my public doc would NEVER put me on brand, so I just switched to provigil, which works better for me anyway....

Anna
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Anna

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#18 Classically_James

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Posted 02 May 2010 - 10:21 AM

No, Ativan, while shorter-acting than Valium, has an onset time of 2-4 hours (but usually affects me much faster than that). Valium's normal onset of action is within 1-2 hours. For me, Valium will always remain my favorite and personally most calming and effective benzodiazapine.
Klonopin's onset of action can take practically forever, up to 4 hours.

James
  • 0

Diagnoses:

1. Major Depressive Disorder (MDD - atypical type)

2. Seasonal Affective Disorder (SAD)

3. Borderline Personality Disorder (BPD)(in partial remission)

4. Cotard's Delusion (removed prior to DSM IV in 1994(in partial remission)  

 

Medications:

1 Cymbalta 60 mg

2. Abilify 10 ng

3. Soma 350 mg TID

4. Lunesta 3 mg

5. Forfivo XL 450 mg


#19 therapeuticbrigg84

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Posted 02 May 2010 - 11:59 AM

not if taken sublingually-klonopin

dx: schizotypal personality disorder, dystonic neck and back pain, GERD. a bit of TD, akathisia, dysmorphic thoughts, affect is questionable

seroquel and inderal 60mg made me fatigued/ depressed. may hafta try lopressor or bisoprolol

inderal interacts with ssris and anti-psychs.

success HCTZ not only lowers my blood pressure and pulse more effectively. but it also has helped with the headaches ive been having. i should see a doctor about this.

[color="#0000FF"]rx: klonopin .5-1 prn, omega 3 fish oil, vitamin D3 iu, albuterol sulfate inhaler, magnesium hydroxide(for the constipationg)

in flux: seroquel 50mg
up and coming: nuvigil

looking into injectables.


artane 2 mg PRN(rare), trazodone 50mg PRN, lyrica PRN?



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